Q5AMG5

PR
Gene name
RAT1 (CAALFM_C401080WA, CaO19.12150, CaO19.4681)
Protein name
5'-3' exoribonuclease 2
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C401080WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

813-917 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5AMG5

Entry ID Method Resolution Chain Position Source
AF-Q5AMG5-F1 Predicted AlphaFoldDB

No variants for Q5AMG5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5AMG5

No associated diseases with Q5AMG5

2 regional properties for Q5AMG5

Type Name Position InterPro Accession
domain Xrn1, N-terminal 1 - 250 IPR004859
domain Xrn1, helical domain 308 - 816 IPR041412

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
5'-3' exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.
DNA strand exchange activity Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
microtubule binding Binding to a microtubule, a filament composed of tubulin monomers.
RNA binding Binding to an RNA molecule or a portion thereof.

4 GO annotations of biological process

Name Definition
DNA-templated transcription termination The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
nuclear-transcribed mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGVPALFRWL SRKYPKIISP VVEEEDHEIG GAKYENPNPN GEIDNLYLDM NGIVHPCSHP
70 80 90 100 110 120
EHKKPPETED EMFLDIFKYT DRVLMMARPR KVLMIAVDGV APRAKMNQQR ARRFRAAKDA
130 140 150 160 170 180
ELKAKQLEIE VQERELRGEI INDAIKGKKQ WDSNAITPGT PFMDRLAEAL RYWVAYKLSS
190 200 210 220 230 240
DPGWANLQVI ISDATVPGEG EHKLMSFIRS QRSDPQYDPN TKHCIYGLDA DLIFLGLATH
250 260 270 280 290 300
EPHFRVLRED VFASQDKKFT IKDQIADANS NGDTVAKEDK KPFLWLHVNV LREYLQVELF
310 320 330 340 350 360
TPRMSFPFEL ERAIDDWVFL CFFAGNDFLP HLPSLDVRDN GIDTLVQCWK RSLPILKDYV
370 380 390 400 410 420
TCDGKLNLKS VEVLMSNLAY KESEIFKNKH AAEQRREENN KRRKLAQEQE RALKRVYSSQ
430 440 450 460 470 480
VSKGKDKAPL TADVNMPLMD TSGQNVEGYA NLTNSDIVQN RAILTKANLA NSDAAAELKK
490 500 510 520 530 540
LIDSKKTQVT VVQDQIATDS SANSETTTSE SELEEIQSDN SLKRKLEPEE DKQTQSDDIK
550 560 570 580 590 600
LWEPGYNKRY YEAKFHCQSD EEIEQTKRDV VRHYVEGIAW VALYYYQGCP SWNWYFPYHY
610 620 630 640 650 660
APFAADFTNL EELFPEGVKF KLGEPFRPFE QLMSVLPAAS GHTLPQVFRD LMSNPDSEII
670 680 690 700 710 720
DFYPEEFEID MNGKKMSWQG IPLLPFIDEK RLLDAVQKKY ELLTPDEKSR NTNKEAELFI
730 740 750 760 770 780
SPANKNFSKF SEKLYKENEN EVTFKYAKSG LSGKIFKLGT FNPEGVFNFP LNEGYMPNVN
790 800 810 820 830 840
NSDYFQAIYH FPKTKTGKSM ILNGHIAPLP ALTTADKNDL LYQLDKFNNR RNGGRFNSTL
850 860 870 880 890 900
DNSDYINKGP AGKELYKTYS MRRGGYRSYL QYLTNGHHPD HQSQNSQYLS YGQQKPYGGQ
910 920 930 940 950 960
GSYNQQGYYN QQGRYNQQGN NYNQQGRYSQ QSQYNQYRSN TQRFNNNQNY NQSSNNSRSG
YLPPRPQR