Q5ALY0
Gene name |
CLB2 (CYB1, CAALFM_C201410CA, CaO19.1446, CaO19.9021) |
Protein name |
G2/mitotic-specific cyclin CLB2 |
Names |
|
Species |
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
KEGG Pathway |
cal:CAALFM_C201410CA |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5ALY0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5ALY0-F1 | Predicted | AlphaFoldDB |
No variants for Q5ALY0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5ALY0 | |||||
No associated diseases with Q5ALY0
4 regional properties for Q5ALY0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cyclin, C-terminal domain | 336 - 452 | IPR004367 |
| domain | Cyclin, N-terminal | 208 - 334 | IPR006671 |
| domain | Cyclin-like domain | 243 - 327 | IPR013763-1 |
| domain | Cyclin-like domain | 340 - 423 | IPR013763-2 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cyclin-dependent protein kinase holoenzyme complex | Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cyclin-dependent protein serine/threonine kinase regulator activity | Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| filamentous growth | The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. |
| G2/M transition of mitotic cell cycle | The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. |
| mitotic cell cycle phase transition | The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase. |
| regulation of cyclin-dependent protein serine/threonine kinase activity | Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. |
| regulation of mitotic cell cycle | Any process that modulates the rate or extent of progress through the mitotic cell cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPQVTKTNNE | NEFRLTRSKV | QHQESISTIK | NTTISNSQHK | QQTQQQISSP | PQVSVTSSEG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSHVNTRQYL | GDVSNQYITN | AKPTNKRKPL | GGDNAPLQKQ | QHRPSRPIPI | ASDNNNNGST |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SSSSNSSNNN | NNDANRLASL | AVPSRLPQKR | QATESSTNLV | EKLRVPQPEV | GERSQSYHKK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SRLIDYEWQD | LDEEDSDDQL | MVSEYVNEIF | SYYYELETRM | LPDPQYLFKQ | TLLKPRMRSI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LVDWLVEMHL | KFKLLPESLF | LAVNVMDRFM | SVEVVQIDKL | QLLATAALFT | AAKYEEVFSP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SVKNYAYFTD | GSYTPEEVVQ | AEKYMLTILN | FDLNYPNPMN | FLRRISKADD | YDVQSRTLGK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLLEITIVDY | KFIGMRPSLC | CASAMYLARL | ILGKLPVWNG | NLIHYSGGYR | ISDMRECIEL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| MFQYLIAPIE | HDEFFKKYAM | RKFMRASTLC | RNWAKKFQAS | GRDLFDERLS | THRLTLEDDD |
| 490 | |||||
| EEEEIVVAEA | EE |