Q5AD56

PR
Gene name
NOT3 (NOT31, CAALFM_C201130WA, CaO19.2012, CaO19.9563)
Protein name
General negative regulator of transcription subunit 3
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C201130WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-431 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5AD56

Entry ID Method Resolution Chain Position Source
AF-Q5AD56-F1 Predicted AlphaFoldDB

No variants for Q5AD56

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5AD56

No associated diseases with Q5AD56

1 regional properties for Q5AD56

Type Name Position InterPro Accession
domain CCR4-Not complex component, Not N-terminal domain 2 - 275 IPR007207

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
CCR4-NOT core complex The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
P-body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
nuclear-transcribed mRNA poly(A) tail shortening Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNRKLQKEI DIIFKKIQEG LQDFDYHYER YESIQNTEDD SDNQREKEKL ANDLKKEIKK
70 80 90 100 110 120
LQKFREQIKH WLQNDTVHTL GPVGTSYESK LAENKSLIED SMETYKLVEK QSKLKTFSNQ
130 140 150 160 170 180
SIMMTFMDST NGDDDDDDDD SDDDELFSGS DEDEEDEYSD LPEDAVNAIH FFKDSILQLR
190 200 210 220 230 240
EQTHKLDHEY EKLAAKKLRK NNLATIEAKK EKIQSTIGNN KFHQKKLKKL LRQLTSGVVT
250 260 270 280 290 300
EFNLIWLLKD DLNKYLESNG DYEFTRETEL YDDIFNQIAA VEEDYSEIHE DNHDHSHSHL
310 320 330 340 350 360
EKTSTANGTH HESATTTATA AKNSSVTTRT SPSPILTKAN GHIKELSVES GSPTTSRSKL
370 380 390 400 410 420
SKIHTNTSQS STHSNTSSST HAQAPRQSPE LTSPAIVKTL RPATAPSKPV GTLKWSAAAA
430 440 450 460 470 480
AAIPDVQEKP ELVETESNGS SVHKTVSKDQ YEEKINYQSP APTQQQQQPQ TSVESKTLST
490 500 510 520 530 540
TQSLASSITD NINLDKYKEV IKNSNLTKTE LGLFSDMNLA RVPPGIQDLV ISFASKRNND
550 560 570 580 590 600
NFKVLVDSTE FNQFALPLHK PYLPEIVQPS YYSQYTSTSF KHPTPLVKFQ SYWNQVRANF
610 620 630 640 650 660
GFQKLMDEIK SLTLQNNADN LPIIAELTFV LFYGFYYGVT PAENLIAESY LFELGWKPYK
670 680 690 700 710 720
NQSEDGSNNL STGSISLSDI NGSKSKSNRS SNYYFWFKRV KLISRGEDMG QPSNIEFGDY
730 740 750
QVFDLSFWEI FVKYGFKFDY NFCQMEPSKT LF