Q5ACX1

PR
Gene name
RAD5 (CAALFM_C200350WA, CaO19.2097, CaO19.9644)
Protein name
DNA repair protein RAD5
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C200350WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-204 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q5ACX1

Entry ID Method Resolution Chain Position Source

No variants for Q5ACX1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ACX1

No associated diseases with Q5ACX1

6 regional properties for Q5ACX1

Type Name Position InterPro Accession
domain SNF2, N-terminal 367 - 760 IPR000330
domain Helicase, C-terminal 913 - 1071 IPR001650
domain Zinc finger, RING-type 814 - 863 IPR001841
domain Helicase superfamily 1/2, ATP-binding domain 360 - 662 IPR014001
domain HIRAN domain 147 - 245 IPR014905
conserved_site Zinc finger, RING-type, conserved site 834 - 843 IPR017907

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

7 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent activity, acting on DNA Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.
ATP-dependent chromatin remodeler activity An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVIKKRFFK PKEETLPSDE VPDPQSSAEP LHSLFVPDES EEEETTTSPK TNFEKDIIAI
70 80 90 100 110 120
VGDISPIIMK YLYAKYSQKR NGAKFAVTEL LTNPPDVEKL QQDSIASQSA KRPHTIVSYQ
130 140 150 160 170 180
EPPNKKVNIN PDSASSNNEP LMWQRLIGSL NIQAMATXPD HETVEIPGKX KLKRITTKNS
190 200 210 220 230 240
TMANSAIVRV YHNEREIGRI PEDWTRILSP LFDLNIAVFE ASVLEETKSR LSTGDSFVIE
250 260 270 280 290 300
IEVYLTNSSF AKNLDATENP IDLKKSNFDY SKESESEAAL RLRQFAISNL FDRLAIKPLK
310 320 330 340 350 360
VNDDTEDEED ISSQEINSGD VEHPVPEINL DQMKEFYQSN NQLKILEGLP ETTTPPKENF
370 380 390 400 410 420
ALDLRSYQKH GLSWMLAREK ELDVLEMLSN EDKLSSQSRK ELENLGTMNP LWRKYKWPYA
430 440 450 460 470 480
TEATQDPTQN QTEKYFYANM YNGELSLEKP VIKSSLRGGI LADEMGLGKT IATLALVNSV
490 500 510 520 530 540
PYDNFPEPKS DRPYASQTTL IVVPMSLLFQ WKSEFEKCNN NSRHVCRLHY GEDQETNLAW
550 560 570 580 590 600
SLCNPDNSKI PIVMITTYGT VLNEFTRLSK RRNSKGELPK VGLYSVKFFR IILDEGHNIR
610 620 630 640 650 660
NRNTKTAKSV YELQSSRKWI LTGTPIVNRL DDLYSLTKFL ELDPWNNFSY WKTFVTLPFE
670 680 690 700 710 720
QKKISQTLDV VKSILEPIFL RRTKSQKKNG KPLVELPAKE VVIEQIKFND DEEKLYQWFK
730 740 750 760 770 780
DRAYASFAEG IKSGQLLRRY TQILTHILRL RQVCCHVDLI GGAHEMDDEI IEAEQDEDMR
790 800 810 820 830 840
KFLTSIKENQ IRFANDTDVK EKMYNLYGKI KEENECSICT QVPIPYSEMV VTPCAHTFCL
850 860 870 880 890 900
SCILEHLDFQ KELKKEKLCP NCRSPISKYQ LFRIRNQPTK GNEIRFHIQK DAPDYSFQLY
910 920 930 940 950 960
LYDPNRSSSK IQALVRHLKA LHSQSPNSKV IVFSQFSSYL DIIQSELKLA SEEFIVFKFD
970 980 990 1000 1010 1020
GRLNMNDRTK LLESFNQPLE DGKVAILLLS LKAGGVGLNL TTASRAYMMD PWWSPSIEDQ
1030 1040 1050 1060 1070 1080
AIDRIHRIGQ NETVKVVRFI MENSIETKML KIQERKKQIG EAVAAEEEER RKRRIEEIQI
LFEE