Q5ACU6

PR
Gene name
RRP3
Protein name
ATP-dependent rRNA helicase RRP3
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_CR09740WA
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

17-182 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5ACU6

Entry ID Method Resolution Chain Position Source
AF-Q5ACU6-F1 Predicted AlphaFoldDB

No variants for Q5ACU6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ACU6

No associated diseases with Q5ACU6

6 regional properties for Q5ACU6

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 266 - 274 IPR000629
domain Helicase, C-terminal 344 - 492 IPR001650
domain DEAD/DEAH box helicase domain 142 - 309 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 137 - 335 IPR014001
domain RNA helicase, DEAD-box type, Q motif 118 - 146 IPR014014
domain DDX47/Rrp3, DEAD-box helicase domain 119 - 321 IPR044765

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTMMNEKLKK EKKKIFGVIT PFQKYLYTPR IINTVHLIIM SSKGITKKKV KSLKNLDSTK
70 80 90 100 110 120
KLAEKIKQQA LQKQQKQQKQ QEQENANHNQ TESSLSSSSS TTSSSITTID PDAELKFKTF
130 140 150 160 170 180
KELNLVPDLL ESIESMKFTK PTPIQSEAIP HALEGKDIIG LAQTGSGKTA AFAIPILQSL
190 200 210 220 230 240
WHAQQPYFAL VLAPTRELAF QIKDTFDALG SSMGLRSSCI VGGMDMMDQA RDLMRKPHVI
250 260 270 280 290 300
VATPGRIMDH LEHTKGFSLK NLKYLVMDEA DRLLDMDFGP ALDKILKVIP IKRTTYLFSA
310 320 330 340 350 360
TMTNKIEKLQ RASLHNPVRV AVSSKYQTAD NLVQSMMLVN DGYKNTILIH LLNEFMGKSI
370 380 390 400 410 420
IVFTRTVAHA QRTALLARIL GFNAVPLHGQ LSQSQRLGSL NKFKSNQANI LVATDVAARG
430 440 450 460 470 480
LDIPSVDVVI NYDIPTDSKA YIHRVGRTAR AGRSGKSISL ITQYDLEMYL RIESVLGKKL
490 500 510 520 530
PKEDKPPKEV LDALHVHVDK ATAEAIRQTK EIHDKRNGGG GRRRNRDDAD REER