Q5A455

PR
Gene name
SEC23 (SEC231, CAALFM_C405690WA, CaO19.1254, CaO19.8839)
Protein name
Protein transport protein SEC23
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C405690WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

171-248 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5A455

Entry ID Method Resolution Chain Position Source
AF-Q5A455-F1 Predicted AlphaFoldDB

No variants for Q5A455

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5A455

No associated diseases with Q5A455

1 regional properties for Q5A455

Type Name Position InterPro Accession
domain Ribosomal RNA methyltransferase, FtsJ domain 53 - 236 IPR002877

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
endoplasmic reticulum exit site An endoplasmic reticulum part at which COPII-coated vesicles are produced.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

2 GO annotations of molecular function

Name Definition
GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
zinc ion binding Binding to a zinc ion (Zn).

7 GO annotations of biological process

Name Definition
COPII-coated vesicle cargo loading The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
positive regulation of ER to Golgi vesicle-mediated transport Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
positive regulation of GTPase activity Any process that activates or increases the activity of a GTPase.
positive regulation of protein exit from endoplasmic reticulum Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
regulation of COPII vesicle coating Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
reticulophagy The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDFEEAEDIN GIRFAWNAFP STKVEAGKVV VPTGALYTPL KQREDLPIAA YDPIYCSNQS
70 80 90 100 110 120
CKSILNPYCA VDPNGFWRCP LCQYRNPLPA HYHGLNPENL PLELQSTSST IEYITARPVQ
130 140 150 160 170 180
NPPIFTFVID LCQDEDNLQA LIEDIIVSFN YLPPNALIGL ITFGTMIQVH DLGSDKINKS
190 200 210 220 230 240
YIFRGDKEYT DKQISEMLNR PISTQLMQQQ QQQPGQMNPQ LANSLTRFFL PLEDVEFQLT
250 260 270 280 290 300
SILENLSKDP WAVANGARPL RSTGSALNIA VNLLGLTYPG FGARVMLFAA GPCTLNPGMI
310 320 330 340 350 360
VGNQLKEPIR SHSDIDKDNA KHFKKATKLY ENIAAKAVKN CHTVDIFAGC YDQIGMLEMK
370 380 390 400 410 420
NLCNLTGGTL LLTDAFTTSI FKRSFLRLFN KDDEGYLLMG FNGNLEVRTS KELKISGLIG
430 440 450 460 470 480
NASSLQVKSA NVSENELGLG GSSSYRLCST SPRHTYAVFF DVVNNQQLPP NAQSYIQFIT
490 500 510 520 530 540
HYQHSSGTYR VRVTTVSNFL TSDEQTLTNS FDQEAAAVLM ARITLFKAEQ DDGADVLRWV
550 560 570 580 590 600
DRMLIRLCQK FADYRKDQQE SFRLGPQFQL YPQFIYYLRR SQFLQVFNNS PDETAFYRHV
610 620 630 640 650 660
LLVEDTNNSL IMIQPTLTSF TLDGEPEAVL LDSVSIKDDR ILLLDTFFHI LIFHGKTISQ
670 680 690 700 710 720
WRKANYQDLP EYSNFKELLE FPKKEAAELL HDRYPLPRFI DTEEGGSQAR FLYSKLNPSV
730 740 750 760
TYNTNDFIGG GGAGGGAIVL TDDVSLQVFM SHLQKLVVSG SS