Q5A449

PR
Gene name
LEA1 (CAALFM_C405750CA, CaO19.1260, CaO19.8845)
Protein name
U2 small nuclear ribonucleoprotein A'
Names
U2 snRNP A'
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C405750CA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

122-233 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5A449

Entry ID Method Resolution Chain Position Source
AF-Q5A449-F1 Predicted AlphaFoldDB

No variants for Q5A449

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5A449

No associated diseases with Q5A449

1 regional properties for Q5A449

Type Name Position InterPro Accession
repeat Leucine-rich repeat 65 - 86 IPR001611

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
U2 snRNP A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes.
U2-type prespliceosome A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.

1 GO annotations of molecular function

Name Definition
U2 snRNA binding Binding to a U2 small nuclear RNA (U2 snRNA).

1 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLTAQVINE APEILNPEGK LTLLLRDLQI TELENLAITQ NKYQVIDLSN NDLISLGNIP
70 80 90 100 110 120
KRFNNLQCLL LSNNNISYID DESFPSDNHI TSITLFNNNI YQFQKSFKDK FPKLETLILL
130 140 150 160 170 180
GNPITEMENY RYFIIWLIPS LKVLDFKKVK QAERKTSEDM FGTNRDEFNS LAQQMFKNEN
190 200 210 220 230
TEIKLDGKSD RQVKNFVKKM TDEERQQLLK KLETATSIEE IERIENDLKE GAV