Q5A013

PR
Gene name
EFM7
Protein name
Protein N-terminal and lysine N-methyltransferase EFM7
Names
Elongation factor methyltransferase 7
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_CR03760WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-65 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5A013

Entry ID Method Resolution Chain Position Source
AF-Q5A013-F1 Predicted AlphaFoldDB

No variants for Q5A013

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5A013

No associated diseases with Q5A013

No regional properties for Q5A013

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5A013

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
N-terminal protein N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
protein-lysine N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.

2 GO annotations of biological process

Name Definition
N-terminal peptidyl-glycine methylation The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
peptidyl-lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEDEISIEG DLFEEPEGFL PERPSSHFST YKRKIPNAEP QEITMKLVGH NPLYGHLLWN
70 80 90 100 110 120
AGIYTADYLD KHSDTLVQGK KILELGAASA LPSLVCSLNH AKEVIVTDYP DPDLLSHMEY
130 140 150 160 170 180
SFNDLKEKTK YELSPWKVKG YIWGHDLGEL LFDEPGRKLA EEEKFDLIIL SDLVFNHSEH
190 200 210 220 230 240
HKLLDTCRQS LKRNGGKCLV VFSPHRPYLL QDDLSFFETA KQYQFKTEKI EMVTWKPMFE
250 260
EDEETADIRA RVYAFFLIPE WE