Q59ZZ6

PR
Gene name
DEM1 (EXO5, CAALFM_CR03490WA, CaO19.11870, CaO19.4392)
Protein name
Exonuclease V, mitochondrial
Names
Exo V, Defects in morphology protein 1
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_CR03490WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q59ZZ6

Entry ID Method Resolution Chain Position Source
AF-Q59ZZ6-F1 Predicted AlphaFoldDB

No variants for Q59ZZ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59ZZ6

No associated diseases with Q59ZZ6

No regional properties for Q59ZZ6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q59ZZ6

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.
single-stranded DNA 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.

1 GO annotations of biological process

Name Definition
interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRFWHFKKF YFTSCYSMQR MRGKIFKNEP LVPMNVTSEH EQVQSISKEE SRSLSSNDLN
70 80 90 100 110 120
LSADSELQLE SEPEIESEQL KNHEDVYEII RSMVLAADTT LPRLSNNSLT GIYNHWKLNP
130 140 150 160 170 180
NDDLPLYNPT KYTPYEFHSQ YNQDRSYIIT PRLSVTKLLV SSWCELRSFY QVYSGSVRLP
190 200 210 220 230 240
STKAMTQGTK LHSKLEAEVH PEIDTTEIEQ FLISNAMSLR ELQTTVPAEE ETVVIDLGEV
250 260 270 280 290 300
EQLAVDWAEM LIERLFSLIM GAEAREILLH GYLNLKNRSF VTNKDEIRES SSVLVSGIVD
310 320 330 340 350 360
YIKLQNVTNP SDGTLFDDIH GFVDSAFDQV DNVPLVDLSQ FLPEAKQILQ NYDFRLTFTD
370 380 390 400 410 420
VKTRSARQIP RQESVLEAAK FQTFYYRHFF HLLSRDSRFT YFSLIENAER RGHDVDKPLS
430 440 450 460 470 480
ILTTISLLRK HYHIFFKDFV KLANGEPIGF SPFDDSAKSI PYDFVSMFQS SDEFSLANPN
490 500 510 520 530 540
HNHFLEQISA IDGIEYDSIL SPLLKVWKTP PTLRYLAARA SQLFNVFNEN IGDITSVEYR
550 560 570 580 590 600
YNKTSELLSE KVYDYNFSEF QAEVESASKF WNGEREVIPT EDLSRCSYCE FQSKCMVAGG
610 620
KTTEAVEKKT IGPKIRQFLN ECESSSKG