Q59YS7

PR
Gene name
MNN14 (CAALFM_C305610WA, CaO19.6996)
Protein name
Putative alpha-1,3-mannosyltransferase MNN14
Names
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_C305610WA
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

118-194 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q59YS7

Entry ID Method Resolution Chain Position Source
AF-Q59YS7-F1 Predicted AlphaFoldDB

No variants for Q59YS7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59YS7

No associated diseases with Q59YS7

No regional properties for Q59YS7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q59YS7

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
alpha-1,3-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.

3 GO annotations of biological process

Name Definition
mannan biosynthetic process The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.
protein mannosylation The addition of a mannose residue to a protein acceptor molecule.
protein O-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLLSIPYQS KSKLWIAIFL VVWSLISMHF IWQSQANSGL ILKNELSSTS SIPHEFEMLI
70 80 90 100 110 120
DTNYPKFKPT SGHSGSQTYS NLFKNQDRNA AIFTILKNFD LEQRCQLYFK NVKNDKLIVD
130 140 150 160 170 180
PDHDFKFDRF DYLNWDEYRD ESIKRLKGDN DEFVATSSDL DTIKKNFDKA KSRIASDLQL
190 200 210 220 230 240
LHDYFSHIKI YNQCYIDRNT SFIKKQHELI DGLNWKTSFK RSSFLSGKQI VTEQQMYPWL
250 260 270 280 290 300
SQKSPEYNCL ATGQTTKFAA NKNSFLNTLK NNLNGKGIVM TIADAHIDYC IRLIHLLRYL
310 320 330 340 350 360
KNTLPIQIIY TSNDLSAESK SQLHQASVSD FDGLPQQNIT LVNVTPAIKP QYLHKFNEFG
370 380 390 400 410 420
NKILAILFNT FEEMIFIDAD AILIENPEKF FQLTKYKNSG ALFFRDRNTS EYRPDHDIEM
430 440 450 460 470 480
FLKLMNSQYD EIIFGLLQIT EKTMSIPLFD RKISHVMESG LVLLNRKVHF SQPLIMANMN
490 500 510 520 530 540
FFEPIRERVY GDKEMFWLSL SIIGDENYQF NSHPAAAIGQ LTTYQERVKT FENPPSSFKS
550 560 570 580 590 600
QEICANHPAH ISDEDNHTLL WFNSGFQFCN QLEKVNYEDE FSHKERYSQF DTIDKFKTFW
610 620 630 640 650 660
QSSLVIESAI IPPENTNSNG GDGYEPSVSW KHMEPYCAGY TWCAYSSIGN GDQANDRGLV
670 680
INYSPEEIEH FKKLGEIWMR GYNYL