Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q59PP0

Entry ID Method Resolution Chain Position Source
AF-Q59PP0-F1 Predicted AlphaFoldDB

No variants for Q59PP0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59PP0

No associated diseases with Q59PP0

2 regional properties for Q59PP0

Type Name Position InterPro Accession
domain DNA mismatch repair protein HSM3, C-terminal domain 313 - 459 IPR040752
domain DNA mismatch repair protein HSM3, N-terminal domain 8 - 240 IPR041335

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLDELSYKVL TNLETSYERK QPLGSKLIDR YTLTIDQSTV AQQSYFEQII PAINRILMNS
70 80 90 100 110 120
EAHVIDPDNV LIRLLPEILS HLSFEQILMY YPNDFILHFL FEEKLENVSV ICLEVILLNL
130 140 150 160 170 180
QEPETLQFLR DNNVISRLLR EVYFKKTPIS VLNKIERLIT VLNGIEEINL LESCLPILKK
190 200 210 220 230 240
IRDQGNTVLL SRYLDLVNLL LRYLPEFSPH LYSFTKQEFL KYQDDPLFLI LLIQFYVKLV
250 260 270 280 290 300
RLKAPVDLSL PLSDILSLYD KFDLLVKNEV VELVAQLSFT QSYTDILFKS QIFKTHNLLE
310 320 330 340 350 360
VFEKTENSDI RLLSKANPQV IYELNNSIYP DVLAHLNLFT NNLYFPILLN FMSSTTIFYQ
370 380 390 400 410 420
LKLHLNNEKL SQLPMDKLFK LLLEMSTHNH SKEHLFNNLP TIMSTNLLET EDLRNNELWN
430 440 450 460 470
LKLEILQNLL NDDSVPGFEF WHQELTRNYE LMTFGRVFRN AAPRVDIIDE TA