Q59KI0

PR
Gene name
UGP1 (CAALFM_CR04660CA, CaO19.1738, CaO19.9305)
Protein name
UTP--glucose-1-phosphate uridylyltransferase
Names
UDP-glucose pyrophosphorylase, UDPGP, UGPase
Species
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
KEGG Pathway
cal:CAALFM_CR04660CA
EC number
2.7.7.9: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-98 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q59KI0

Entry ID Method Resolution Chain Position Source
AF-Q59KI0-F1 Predicted AlphaFoldDB

No variants for Q59KI0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59KI0

No associated diseases with Q59KI0

1 regional properties for Q59KI0

Type Name Position InterPro Accession
ptm Intein N-terminal splicing region 119 - 258 IPR006141

Functions

Description
EC Number 2.7.7.9 Nucleotidyltransferases
Subcellular Localization
  • Secreted, cell wall
  • Localizes to yeast but not hyphal cell surface
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
UTP:glucose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.

6 GO annotations of biological process

Name Definition
(1->6)-beta-D-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
glycogen biosynthetic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
glycogen metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
intein-mediated protein splicing The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.
trehalose biosynthetic process The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
UDP-glucose metabolic process The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATTGKRHAK SQSTYAFDNT ATNVTASQMR NALNNLADTV ENPEQTTRFE NEMDNFFTLF
70 80 90 100 110 120
RRYLTEKASG STLDWDKIRS PSSDEVVEYG DLNSANNSAN LSKLAVLKLN GGLGTSMGCV
130 140 150 160 170 180
GPKSVIEVRD GNNFLDLAVR QIEHLNRKYD ADVPLLLMNS FNTDADTEKI IKKYQSHRIR
190 200 210 220 230 240
VKTFNQSRFP RIYKDSLLPV PESFDDSLEA WYPPGHGDLF EALVQSGELD ALLAQGREIL
250 260 270 280 290 300
FVSNGDNLGA TVDSKILDHM IETGAEYIME LTPKTRADVK GGTLINYQGE VRLLEIAQVP
310 320 330 340 350 360
KEHVEEFKSI KKFKYFNTNN LWINLRAIKK LVEANAIEVE IIPNQKTISH GKSDINVLQL
370 380 390 400 410 420
ETAVGAAIRH FKGAHGVVVP RSRFLPVKTC SDLLLVKSDL FYLEHGALVL DPTRDGFSNP
430 440 450 460 470 480
LIKLGSHFKK VSGFQSRIPY IPKILELDHL TITGNVTIGK GVQLKGTVII VCNDGDKIDI
490
PNGAILENVV VTGNLTILEH