Q59754

PR
Gene name
ppdK (podA, R00932, SMc00025)
Protein name
Pyruvate, phosphate dikinase
Names
Pyruvate, orthophosphate dikinase
Species
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
KEGG Pathway
sme:SMc00025
EC number
2.7.9.1: Phosphotransferases with paired acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q59754

Entry ID Method Resolution Chain Position Source
AF-Q59754-F1 Predicted AlphaFoldDB

No variants for Q59754

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59754

No associated diseases with Q59754

6 regional properties for Q59754

Type Name Position InterPro Accession
domain PEP-utilising enzyme, C-terminal 530 - 882 IPR000121
domain Pyruvate phosphate dikinase, AMP/ATP-binding 22 - 296 IPR002192-1
domain Pyruvate phosphate dikinase, AMP/ATP-binding 312 - 371 IPR002192-2
domain PEP-utilising enzyme, mobile domain 436 - 516 IPR008279
active_site PEP-utilising enzyme, active site 463 - 474 IPR018274
conserved_site PEP-utilising enzyme, conserved site 774 - 792 IPR023151

Functions

Description
EC Number 2.7.9.1 Phosphotransferases with paired acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
metal ion binding Binding to a metal ion.
pyruvate, phosphate dikinase activity Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate.

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
pyruvate metabolic process The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKWVYTFGA GQAEGSAEDR DRLGGKGANL AEMCNLGLPV PPGLTIVTAA CNSYLEKGRS
70 80 90 100 110 120
MPEGLREQVR EGITRMEKIT GRVFGDTNRP LLLSVRSGAR ASMPGMMDTV LNLGLNDQSV
130 140 150 160 170 180
HALGHDAGDA RFAWDSYRRF IQMYGDVVMG VDHEVFEEVL EDEKARLGHE QDTELSAVEW
190 200 210 220 230 240
QHVISRYKEA IEEVLGLPFP QDPEVQLWGA IGAVFSSWMN PRAITYRHLH GIPAGWGTAV
250 260 270 280 290 300
NVQAMVFGNL GNSSATGVAF TRNPSTGEKE LYGEFLVNAQ GEDVVAGIRT PQNITEAARI
310 320 330 340 350 360
ASGSDKPSLE KLMPEAFAEF EKICNALERH YRDMQDIEFT IERGKLWMLQ TRSGKRTAKS
370 380 390 400 410 420
ALKIAVDMAE EGLISKEEAV ARIDPASLDQ LLHPTIDPHA RRDIIGSGLP ASPGAATGEI
430 440 450 460 470 480
VFSSDEAVQA VKEGRKVILV RVETSPEDIH GMHAAEGILT TRGGMTSHAA VVARGMGTPC
490 500 510 520 530 540
VSGAGSIRVD QRNELLIAAS VTLRKGDVIT IDGSSGQVLK GEIPMLQPEL SGDFGKIMQW
550 560 570 580 590 600
ADASRRMTVR TNAETPADAR AARSFGAEGI GLCRTEHMFF EDDRINVMRE MILAEDEAGR
610 620 630 640 650 660
RTALAKLLPM QRSDFVELFS IMHGLPVTIR LLDPPLHEFL PKTDEEIAEV ARVLTIDPAE
670 680 690 700 710 720
LRQRVDALHE FNPMLGHRGC RLAISYPEIA EMQARAIFEA AVQAAHDTGA AVVPEIMVPL
730 740 750 760 770 780
VGLRAELDYV KARIEAVAKE VIGEAGVNID YLIGTMIELP RAALRADTIA ESADFFSFGT
790 800 810 820 830 840
NDLTQTTFGI SRDDAALFLA TYQQKGIIEQ DPFVSLDFEG VGELIQIAAE RGRRTKNGLK
850 860 870 880 890
LGICGEHGGD PASIRFCEEA GLDYVSCSPF RVPIARLAAA QATINGREVA EVQALAAS