Q59635

PR
Gene name
katB (PA4613)
Protein name
Catalase
Names
Paraquat-inducible catalase isozyme B
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA4613
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q59635

Entry ID Method Resolution Chain Position Source
AF-Q59635-F1 Predicted AlphaFoldDB

No variants for Q59635

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59635

No associated diseases with Q59635

4 regional properties for Q59635

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 357 - 365 IPR002226
domain Catalase immune-responsive domain 435 - 495 IPR010582
domain Catalase core domain 34 - 414 IPR011614
active_site Catalase active site 70 - 86 IPR024708

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Periplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
periplasmic space The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNPSLNAFRP GRLLVAASLT ASLLSLSVQA ATLTRDNGAP VGDNQNSQTA GPNGSVLLQD
70 80 90 100 110 120
VQLLQKLQRF DRERIPERVV HARGTGAHGE FVASADISDL SMAKVFRKGE KTPVFVRFSA
130 140 150 160 170 180
VVHGNHSPET LRDPRGFATK FYTADGNWDL VGNNFPTFFI RDAIKFPDMV HAFKPDPRSN
190 200 210 220 230 240
LDDDSRRFDF FSHVPEATRT LTLLYSNEGT PASYREMDGN SVHAYKLVNA RGEVHYVKFH
250 260 270 280 290 300
WKSLQGQKNL DPKQVAEVQG RDYSHMTNDL VSAIRKGDFP KWDLYIQVLK PEDLAKFDFD
310 320 330 340 350 360
PLDATKIWPG IPERKIGQMV LNRNVDNFFQ ETEQVAMAPS NLVPGIEPSE DRLLQGRLFA
370 380 390 400 410 420
YADTQMYRVG ANGLGLPVNR PRSEVNTVNQ DGALNAGHST SGVNYQPSRL DPREEQASAR
430 440 450 460 470 480
YVRTPLSGTT QQAKIQREQN FKQTGELFRS YGKKDQADLI ASLGGALAIT DDESKYIMLS
490 500 510
YFYKADSDYG TGLAKVAGAD LQRVRQLAAK LQD