Q59228

PR
Gene name
aspC
Protein name
Aspartate aminotransferase
Names
AspAT, Transaminase A
Species
Geobacillus stearothermophilus (Bacillus stearothermophilus)
KEGG Pathway
EC number
2.6.1.1: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q59228

Entry ID Method Resolution Chain Position Source
AF-Q59228-F1 Predicted AlphaFoldDB

No variants for Q59228

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59228

No associated diseases with Q59228

2 regional properties for Q59228

Type Name Position InterPro Accession
binding_site Aminotransferases, class-I, pyridoxal-phosphate-binding site 234 - 247 IPR004838
domain Aminotransferase, class I/classII 31 - 385 IPR004839

Functions

Description
EC Number 2.6.1.1 Transaminases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
L-aspartate:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

1 GO annotations of biological process

Name Definition
biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLAKRVASL TPSATLAITE KAKELKAAGH DVIGLGAGEP DFNTPQHILD AAIKAMNEGH
70 80 90 100 110 120
TKYTPSGGLP ALKEEIIKKF ARDQGLDYEP AEVIVCVGAK HALYTLFQVL LDEGDEVIIP
130 140 150 160 170 180
TPYWVSYPEQ VKLAGGVPVY VEGLEQNHFK ITPEQLKQAI TPRTKAVIIN SPSNPTGMIY
190 200 210 220 230 240
TAEELKALGE VCLAHGVLIV SDEIYEKLTY GGAKHVSIAE LSPELKAQTV IINGVSKSHS
250 260 270 280 290 300
MTGWRIGYAA GPKDIIKAMT DLASHSTSNP TSIAQYAAIA AYSGPQEPVE QMRQAFEQRL
310 320 330 340 350 360
NIIYDKLVQI PGFTCVKPQG AFYLFPNARE AAAMAGCRTV DEFVAALLEE AKVALVPGSG
370 380 390
FGAPDNVRLS YATSLDALET AVERIHRFME ARA