Q59204
Gene name |
cyp114 (blr2145) |
Protein name |
Cytochrome P450 BJ-3 |
Names |
Cytochrome P450 114 |
Species |
Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) |
KEGG Pathway |
bja:blr2145 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q59204
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q59204-F1 | Predicted | AlphaFoldDB |
No variants for Q59204
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q59204 | |||||
No associated diseases with Q59204
1 regional properties for Q59204
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 369 - 378 | IPR017972 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| cholest-4-en-3-one 26-monooxygenase activity | Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| steroid hydroxylase activity | Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cholesterol catabolic process | The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDVQETTAAC | RDAFAELASP | ACIHDPYPFM | RWLREHDPVH | RAASGLFLLS | RHADIFWAFK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATGDAFRGPA | PGELARYFSR | AATSPSLNLL | ASTLAMKDPP | THTRLRRLIS | RDFTMGQIDN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRPSIARIVA | ARLDGITPAL | ERGEAVDLHR | EFALALPMLV | FAELFGMPQD | DMFELAAGIG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TILEGLGPHA | SDPQLAAADA | ASARVQAYFG | DLIQRKRTDP | RRDIVSMLVG | AHDDDADTLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DAELISMLWG | MLLGGFVTTA | ASIDHAVLAM | LAYPEQRHWL | QADAARVRAF | VEEVLRCDAP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AMFSSIPRIA | QRDIELGGVV | IPKNADVRVL | IASGNRDPDA | FADPDRFDPA | RFYGTSPGMS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TDGKIMLSFG | HGIHFCLGAQ | LARVQLAESL | PRIQARFPTL | AFAGQPTREP | SAFLRTFRTL |
| PVRLHAQGS |