Q59109

PR
Gene name
dsrA (AF_0423)
Protein name
Sulfite reductase, dissimilatory-type subunit alpha
Names
Dissimilatory sulfite reductase subunit alpha, Hydrogensulfite reductase subunit alpha
Species
Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)
KEGG Pathway
afu:AF_0423
EC number
1.8.99.5: With other acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for Q59109

Entry ID Method Resolution Chain Position Source
3MM5 X-ray 180 A A/D 1-418 PDB
3MM6 X-ray 190 A A/D 1-418 PDB
3MM7 X-ray 190 A A/D 1-418 PDB
3MM8 X-ray 228 A A/D 1-418 PDB
3MM9 X-ray 210 A A/D 1-418 PDB
3MMA X-ray 230 A A/D 1-418 PDB
3MMB X-ray 230 A A/D 1-418 PDB
3MMC X-ray 204 A A/D 1-418 PDB
AF-Q59109-F1 Predicted AlphaFoldDB

No variants for Q59109

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q59109

No associated diseases with Q59109

3 regional properties for Q59109

Type Name Position InterPro Accession
domain Nitrite/Sulfite reductase ferredoxin-like domain 91 - 155 IPR005117
domain Nitrite/sulphite reductase 4Fe-4S domain 166 - 381 IPR006067
domain 4Fe-4S ferredoxin-type, iron-sulphur binding domain 277 - 305 IPR017896

Functions

Description
EC Number 1.8.99.5 With other acceptors
Subcellular Localization
  • Membrane
  • Although the protein complex is found in the soluble fraction it may be membrane-associated in vivo
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
hydrogensulfite reductase activity Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSETPLLDEL EKGPWPSFVK EIKKTAELME KAAAEGKDVK MPKGARGLLK QLEISYKDKK
70 80 90 100 110 120
THWKHGGIVS VVGYGGGVIG RYSDLGEQIP EVEHFHTMRI NQPSGWFYST KALRGLCDVW
130 140 150 160 170 180
EKWGSGLTNF HGSTGDIIFL GTRSEYLQPC FEDLGNLEIP FDIGGSGSDL RTPSACMGPA
190 200 210 220 230 240
LCEFACYDTL ELCYDLTMTY QDELHRPMWP YKFKIKCAGC PNDCVASKAR SDFAIIGTWK
250 260 270 280 290 300
DDIKVDQEAV KEYASWMDIE NEVVKLCPTG AIKWDGKELT IDNRECVRCM HCINKMPKAL
310 320 330 340 350 360
KPGDERGATI LIGGKAPFVE GAVIGWVAVP FVEVEKPYDE IKEILEAIWD WWDEEGKFRE
370 380 390 400 410
RIGELIWRKG MREFLKVIGR EADVRMVKAP RNNPFMFFEK DELKPSAYTE ELKKRGMW