Q58CZ0

PR
Gene name
DFFB
Protein name
DNA fragmentation factor subunit beta
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:512730
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-46 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q58CZ0

Entry ID Method Resolution Chain Position Source
AF-Q58CZ0-F1 Predicted AlphaFoldDB

No variants for Q58CZ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q58CZ0

No associated diseases with Q58CZ0

2 regional properties for Q58CZ0

Type Name Position InterPro Accession
domain CIDE-N domain 7 - 83 IPR003508
domain DNA fragmentation factor 40, C-terminal 104 - 325 IPR015311

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
deoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.

1 GO annotations of biological process

Name Definition
apoptotic DNA fragmentation The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAVLRKPKT FKLRSLHSEK KFGVAGRSCE EVLRKGCQRL QLPIPGSRLC LYEDGTELTG
70 80 90 100 110 120
DYFWSAPDNS ELVLLTAGQT WQGFVSDISR FLSVFQEPHA GVIQAARQLL WDERAPLRQK
130 140 150 160 170 180
LLADLLGTVS ENIAAETRAE DPPWFEGLES RFRSKSGYLR YSCESRIRSY LREVTSGASL
190 200 210 220 230 240
VGAEAREEYL RLVGSMQQKL QAAQYNSSYF DRGAKAGRRL CTPEGWFSCQ GPFDVDDCTS
250 260 270 280 290 300
RHSINPYSNR ESRVLFSTWN LDHVIEKKRV VVPALAAAVH DAEGREVDWE YFYRLLFTLE
310 320 330 340
NLKLVHIACH KKTTHKLHCD PSRVYCTPAA PRRKRHARHR L