Q58717
Gene name |
MJ1321 |
Protein name |
Protein argonaute |
Names |
MjAgo |
Species |
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
KEGG Pathway |
mja:MJ_1321 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q58717
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5G5S | X-ray | 229 A | A | 1-713 | PDB |
| 5G5T | X-ray | 285 A | A | 1-713 | PDB |
| AF-Q58717-F1 | Predicted | AlphaFoldDB |
No variants for Q58717
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q58717 | |||||
No associated diseases with Q58717
1 regional properties for Q58717
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Piwi domain | 426 - 699 | IPR003165 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to virus | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVLNKVTYKI | NAYKIKEEFI | PKEVHFYRIK | SFVNEAFNFY | RFVNFYGGMI | INKKDKSFVL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PYKVDNKVLK | YKDGNNEIPI | DIEYIKSLKL | EYVKPEIAEK | LVRGYLKSVH | KIEPELSRII |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KNIRKHKVVE | NIKVESYCEY | EVKKHDGDYY | LILNFRHTAS | ITKHLWDFVN | RDKALLEEYV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GKKIIFKPNP | KVRYTISLVD | APNPQKIEEI | MSHIIKYYKW | SEDMVKSTFG | EIDYNQPIMY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CEEILEPFAP | QFCNLVFYMD | ELDSYILKEL | QSYWRLSNEN | KGKIINEIAK | KLRFIDNTPK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELEFMKFNNT | PLLVKDVNKN | PTKIYSTNTL | FTWIYNQNAK | IYLPYDVPEI | IRNKNLLTYI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LIDEEIKDEL | KAIKDKVNKM | FRNYNKIANK | TELPKFNYAN | RWKYFSTDDI | RGIIKEIKSE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FNDEICFALI | IGKEKYKDND | YYEILKKQLF | DLKIISQNIL | WENWRKDDKG | YMTNNLLIQI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MGKLGIKYFI | LDSKTPYDYI | MGLDTGLGIF | GNHRVGGCTV | VYDSEGKIRR | IQPIETPAPG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ERLHLPYVIE | YLENKANIDM | ENKNILFLRD | GFIQNSERND | LKEISKELNS | NIEVISIRKN |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NKYKVFTSDY | RIGSVFGNDG | IFLPHKTPFG | SNPVKLSTWL | RFNCGNEEGL | KINESIMQLL |
| 670 | 680 | 690 | 700 | 710 | |
| YDLTKMNYSA | LYGEGRYLRI | PAPIHYADKF | VKALGKNWKI | DEELLKHGFL | YFI |