Q58623
Gene name |
MJ1226 |
Protein name |
Putative cation-transporting ATPase MJ1226 |
Names |
|
Species |
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
KEGG Pathway |
mja:MJ_1226 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q58623
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q58623-F1 | Predicted | AlphaFoldDB |
No variants for Q58623
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q58623 | |||||
No associated diseases with Q58623
1 regional properties for Q58623
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Type II/IV secretion system domain | 21 - 169 | IPR001482 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| P-type ion transporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate. |
| P-type proton-exporting transporter activity | Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ion transmembrane transport | A process in which an ion is transported across a membrane. |
| proton export across plasma membrane | The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWGVVMNVEE | IEEEYKTSIK | TGLSTEEAKK | RLKIYGYNEI | PEKKVHPIIK | FLSYFWNPIA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WMIEIAAILS | AIIKHWVDFV | IILILLLVNG | VVGFWEEYKA | ENVIEFLKQK | MALNARVLRD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKWQIIPAKE | LVPGDVVRIR | IGDIVPADII | LVDGDYLVVD | ESALTGESLP | VEKKIGDIAY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SGSIVKKGEM | TGIVKATGLN | TYFGKTVKLV | EKAEKVSSYQ | KMIIKIGDYL | IVLAVILIAI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MVAVELFRGK | SLIETAQFAL | VLAVSAIPAA | MPAVLSITMA | IGALNLAKKD | AIVKKLVAIE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELAGVDILCS | DKTGTLTKNQ | LVCGEIIALN | GFSKEDVVLF | AALASREEDA | DAIDMAILNE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AKKLGLMEKI | KNYKIKKFIP | FDPVIKRTEA | EVTNDEEFKV | SKGAPQVILD | LCNADEELRR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KVEEIVDKLA | ENGYRALGVA | VYKNGRWHFA | GIIPLYDPPR | EDAPLAVKKI | KELGVIIKMV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TGDHVAIAKN | IARMLGIGDK | IISISELLKK | LKRGEIKEEK | FDEIVEEADG | FAEVFPEHKY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KIVDSLQKRG | HLVAMTGDGV | NDAPALKKAD | CGIAVSNATD | AARAAADIVL | LSPGISVIVD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| AIQEARRIFQ | RMESYVIYRI | TETIRILFFV | ELCILILGIY | PITALMIVLL | AILNDIPILA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IAYDNVVEPK | SPVRWRMREI | LMLSTALGLS | GVVSSFLIFY | ISDVFLHLTI | AELQSFVFLK |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LILAGHATIF | VTRIRDRLWK | KPYPSKLLFW | GVMGTNIIGT | IVAAEGIFMA | PIGWDLALFM |
| 790 | 800 | ||||
| WLYAHVWMLI | NDEIKMILLK | RLKID |