Q58539

PR
Gene name
rnp3
Protein name
Ribonuclease P protein component 3
Names
RNase P component 3, Rpp30
Species
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
KEGG Pathway
mja:MJ_1139
EC number
3.1.26.5: Endoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

29-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q58539

Entry ID Method Resolution Chain Position Source
6K0A EM 460 A C/D 1-232 PDB
6K0B EM 430 A C/D 1-232 PDB
AF-Q58539-F1 Predicted AlphaFoldDB

No variants for Q58539

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q58539

No associated diseases with Q58539

2 regional properties for Q58539

Type Name Position InterPro Accession
domain mRNA capping enzyme, adenylation domain 24 - 242 IPR001339
domain mRNA capping enzyme, C-terminal 246 - 374 IPR013846

Functions

Description
EC Number 3.1.26.5 Endoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
ribonuclease P complex A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.

1 GO annotations of molecular function

Name Definition
ribonuclease P activity Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.

1 GO annotations of biological process

Name Definition
tRNA 5'-leader removal Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRIDINRIEK EEDIKLLKEL KWNGFVFYQY DDEFSKDRYE EVKAIAESYK LKVYSGVKIK
70 80 90 100 110 120
TESSKQLRDK VKKFRNKCHI ILIEGGVLKI NRAAVELHDV DILSTPELGR KDSGIDHVLA
130 140 150 160 170 180
RLASNHRVAI ELNFKTLLNK DGYERARTLL FFRNNLKLAK KFDVPVVIST DAENKYQIKN
190 200 210 220 230
PYDLRAFLNT LVEPLYAKKI METAYKICDF RDYLMRDNVV RYGVEIIKEE KE