Q58428
Gene name |
arcS |
Protein name |
Archaeosine synthase |
Names |
Glutamine:preQ0-tRNA amidinotransferase |
Species |
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
KEGG Pathway |
mja:MJ_1022 |
EC number |
2.6.1.97: Transaminases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q58428
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q58428-F1 | Predicted | AlphaFoldDB |
No variants for Q58428
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q58428 | |||||
No associated diseases with Q58428
Functions
| Description | ||
|---|---|---|
| EC Number | 2.6.1.97 | Transaminases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| archaeosine synthase activity | Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA. |
| pentosyltransferase activity | Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| archaeosine-tRNA biosynthetic process | The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs. |
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLEPIAYDIG | RLCKEEDKEL | TPKLIDIDVI | GLSQEKIFYG | IMTPFRCPNS | KSIYELRKSY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VKADGIKMPF | DTFRELTSIF | KKSFIGTVKY | KGNVFKYQIL | NFGKHVDLIE | LEDADLYIIA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGRRLIERKE | LQIIPKIREK | ISPNSAIYSP | AVFPWEIPLL | AYIGVDYFDD | SLAKLYASMG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YKFTKNRAVK | VDSFSFEELY | NNNKKVYEEI | LEEVRIAIKN | GFLRNVVEET | AVSHPYLWAN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YRRYEPDLRN | IPLSKENKII | VTTNINIPEV | KKYLERLDNY | EPYSNIIVLL | PCSSKKPYSI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SQSHQKFIKA | IKSAKVVVEE | VILTSPYGLV | PRALERLVNY | DIPVTGEWSF | EEIELINNCL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KNFLKKVKEK | FDDYIVIAHL | PEHYLEILEL | DDIVITSKGN | PTSEEALKNL | TDTLKKYKEL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TKSKDINKKG | QRIHNIQQLA | EFQFGINFIP | NEIFINHKGQ | IFTKINNKNQ | QIASINPKNG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LLILTLSGGE | LLWNSGGKDI | NYIEVNYEIK | KGSLFPPGFV | DCNENISYND | EVVLIKDDTF |
| 550 | 560 | ||||
| LGIGRALMSG | FEMKKAKHGA | LVNIRNVKS |