Q58138

PR
Gene name
cooS (MJ0728)
Protein name
Carbon monoxide dehydrogenase
Names
CODH
Species
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
KEGG Pathway
mja:MJ_0728
EC number
1.2.7.4: With an iron-sulfur protein as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

565-624 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q58138

Entry ID Method Resolution Chain Position Source
AF-Q58138-F1 Predicted AlphaFoldDB

No variants for Q58138

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q58138

No associated diseases with Q58138

No regional properties for Q58138

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q58138

Functions

Description
EC Number 1.2.7.4 With an iron-sulfur protein as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
carbon-monoxide dehydrogenase (acceptor) activity Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.
carbon-monoxide dehydrogenase (ferredoxin) activity Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin.
hydroxylamine reductase activity Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.
nickel cation binding Binding to a nickel (Ni) cation.
peroxidase activity Catalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O.

3 GO annotations of biological process

Name Definition
generation of precursor metabolites and energy The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKNCIAAIPE VKEMVEKAKL KGIETPHTRF PNQFPKCPYG LKGVYCILCA NGPCRITEKT
70 80 90 100 110 120
PYGVCGATAD VIVARNLCRA VAAGTSCYVH CAENAARALL SAGKGEGSYE IRNEKKLKFL
130 140 150 160 170 180
AKKLGFDANK DAKQLAVEVA EFILDDMYKP RWEKSELVPK LCPEKRLEVF EKLDILPGGA
190 200 210 220 230 240
KGEIVDALTK TSTNLNSNPM DLLVHCLRLG LHAGFTGLLM TCWLNDILFG SPKITVVENG
250 260 270 280 290 300
FSSVKPNNVN IMITGHQHAL IQPLCEAAME EDLIKMAKEA GADEIKIIGA TCNGQDMETR
310 320 330 340 350 360
IAHLPESFVG YIANNFTTEP LVATGLIDAV VSEFNCTFHG LKFVAEKTKT KLICIDDMAY
370 380 390 400 410 420
VEGAEYIPWE PENAKEKARE IIKKAIEAFK ERKGMQKDYY DEKVKSVVGV GEESLVEFLG
430 440 450 460 470 480
GSVKPLIELI ASGKIKGVVG VVGCSNLASG GHDNIIVTLT KELIKRDILV LAGGCVNSPL
490 500 510 520 530 540
KHAGLFDPAS AELAGENLKE VCKSLGIPPV LNFGACLSIA RIEQVAVAIA EELGVDIPDL
550 560 570 580 590 600
PVAASAPQWL EEQALADATY AVDMGFTVHV SPVPFVTGSE LVTKVLTEAV EGLTGGKLIP
610 620
EPNPYKAADL LEQTIMEKRK KLGI