Q58029

PR
Gene name
MJ0612
Protein name
Probable arogenate/prephenate dehydrogenase
Names
Species
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
KEGG Pathway
mja:MJ_0612
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

256-331 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q58029

Entry ID Method Resolution Chain Position Source
AF-Q58029-F1 Predicted AlphaFoldDB

No variants for Q58029

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q58029

No associated diseases with Q58029

2 regional properties for Q58029

Type Name Position InterPro Accession
conserved_site Helix-turn-helix motif 190 - 215 IPR000047
domain Homeobox domain 159 - 223 IPR001356

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
NAD+ binding Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
prephenate dehydrogenase (NAD+) activity Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH.
prephenate dehydrogenase (NADP+) activity Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH.

1 GO annotations of biological process

Name Definition
tyrosine biosynthetic process The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKNTNLTISI IGGTDGLGKW FARYLKNKGF NVIVTGRDIE KGKNVEKELG VEFTNNNIEA
70 80 90 100 110 120
AKKGDIVIVA VPINVTERVI KEVAPHVREG CLLMDITSIK EIPSKAMEEH VKEGVTVIPT
130 140 150 160 170 180
HPMFGPSTPS LLRQVVILTP SEKHKNTEWF NKVYNFLKKE GAKVIVIPPE KHDRIMGIVQ
190 200 210 220 230 240
GLTHFAFISL GATLKELNVD IKESRKFASP IYELMISIIG RIIGQNPYLY ADIQMFNPRI
250 260 270 280 290 300
KEIHETFINQ CKEISEIVKN KDREGFVKIM KEAAKHFGSE AKRGAYYSDK AVFALTSEIE
310 320 330 340 350 360
KLNKLIGKDV AVKNINSNVV HFGVLKDIED DYLILNKNGK EQKFNILRVE VFAGDELSKL
370 380 390 400 410 420
KKKHLEKKYI DVSVLFKKDV DEEVILNLLK KMFDIEIIDV YEGEKIEEGY KSITFRIYGY
430 440
NKDELKNIEK EFLKIIKNIG GKERFK