Q57878
Gene name |
tgtA |
Protein name |
tRNA-guanine(15) transglycosylase |
Names |
7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase |
Species |
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) |
KEGG Pathway |
mja:MJ_0436 |
EC number |
2.4.2.48: Pentosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q57878
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q57878-F1 | Predicted | AlphaFoldDB |
No variants for Q57878
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q57878 | |||||
No associated diseases with Q57878
4 regional properties for Q57878
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.2.48 | Pentosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| pentosyltransferase activity | Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| queuosine biosynthetic process | The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. |
| tRNA wobble guanine modification | The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTFEIKHRDA | MGRIGILNIN | GKKIETPTIM | PVIHPNPKKQ | IVSMDLINKL | ADVIITNSYI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TYKTKHLREI | AEEKGIHKLI | GFDKVIVTDS | GSFQLGVYGD | VEVEPMEIIE | FQERIGVDVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TILDIPTPPD | VDRERAEKEL | EETLKRAKAS | IELKEERGFK | LLLNGTVQGS | TYLDLRQKSA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEMAKLGFDI | YPIGAVVPLM | EQYRYRDVAE | IIINSKMYLP | TNKPVHLFGC | GHPMFFALAV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALGCDLFDSA | AYALYAKDDR | YLTERGTLHL | EEIKDLKAFP | CSCPVCSSYT | PKELASLNKK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERERLLAEHN | LYVTFEEINR | IKQAIRDGSL | WELVEERVRC | HPKLLEAYRV | VRKYIDYIEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FDPVTKKSAF | FYTGIESMFR | PEVLRHKKRL | KRLRYEKVYI | TTVSSSIEKP | YHEHLNVVET |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DVDILIKDPV | FGFIPYYIDT | VYPLSQHEIP | ELFDYEKEIN | KRFVDEFIDW | LKKKIGEDNI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LDIMTYNYYI | NYFSANKKIN | ADALRIRKML | QYQYGFDIID | DELMNKIKVV | RSKTTGRLRQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VLDENGEILF | SVRSNDNLLI | PSEKGAKLLW | KKIPFPKYRV | VVNKEAEEFA | REGRNVFAKF |
| 610 | 620 | 630 | 640 | 650 | |
| VIDCDEELRP | YEEVLVVNED | DELLAYGTTI | LNGIELREFN | YGLAVKVRGG | LKINK |