Q57813

PR
Gene name
MJ0367
Protein name
Probable integrase/recombinase protein MJ0367
Names
Species
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
KEGG Pathway
mja:MJ_0367
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q57813

Entry ID Method Resolution Chain Position Source
AF-Q57813-F1 Predicted AlphaFoldDB

No variants for Q57813

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q57813

No associated diseases with Q57813

4 regional properties for Q57813

Type Name Position InterPro Accession
domain Protein kinase domain 333 - 535 IPR000719
domain Gcp-like domain 1 - 323 IPR000905
active_site Tyrosine-protein kinase, active site 447 - 459 IPR008266
conserved_site Peptidase M22, conserved site 91 - 111 IPR017860

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

5 GO annotations of biological process

Name Definition
DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
establishment of integrated proviral latency A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
viral genome integration into host DNA The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MREKELKHIE NLLLLKVKKE KIEETDKIKE YLKRFEDERR FDGIKESTIK SDLDRLRVFL
70 80 90 100 110 120
DYCINYLGKN PEELKTSDFV KFFNYLDTVR KVSKSSQRKY FLLLKVFYRV LRMYNVIQEF
130 140 150 160 170 180
VEESKDRKRF ARIEIQHYDA VDAEMLNMIL KKIIESGSRT RIRDALIIRL LWDTGCRVSE
190 200 210 220 230 240
VLNLKYKDCD LDNGIFKIRN TKTHEERTVV CSSDTLELLR NYVQFNVRQG SDDYLFQNSQ
250 260 270 280 290 300
GGRVRKEWIS EVFRKAVNEL KEEGKIPKNR RIVIHSIRHG RAVDLLNKGV PIDIVKEYLG
310 320
HKSMNTTLIY AHSKERAESL EFIKKLLRIQ