Q57581

PR
Gene name
eif2a (MJ0117)
Protein name
Translation initiation factor 2 subunit alpha
Names
aIF2-alpha, eIF-2-alpha
Species
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
KEGG Pathway
mja:MJ_0117
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

55-152 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q57581

Entry ID Method Resolution Chain Position Source
AF-Q57581-F1 Predicted AlphaFoldDB

No variants for Q57581

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q57581

No associated diseases with Q57581

3 regional properties for Q57581

Type Name Position InterPro Accession
domain S1 domain 9 - 83 IPR003029
domain RNA-binding domain, S1 10 - 83 IPR022967
domain IF2a, S1-like domain 9 - 84 IPR044126

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ribosome binding Binding to a ribosome.
RNA binding Binding to an RNA molecule or a portion thereof.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFIMRREFPE EGDIVIGTVK DVKPYGAFVE LLEYPGKEGM IHISEVTSGW VKNIRDHVKV
70 80 90 100 110 120
GQRVVAKVLR VDERKGHIDL SLKRVTEQQK RAKVQEWKRF QRASKMLERA AEKLGKSLEE
130 140 150 160 170 180
AWEEVGYLLE DEFGELYNAF ETMVIEGKEV LDDLEISEEW KNVLYEVAKE SIELTNVEVE
190 200 210 220 230 240
GVIEMKSYAP DGIKQIKKAL TTALKANPYE DVEVKITYIG APKYRVVVIA PDYKSGEEVF
250 260
KKVCEKAVAT IKKLGGEGTY YRESKK