Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q57568

Entry ID Method Resolution Chain Position Source
AF-Q57568-F1 Predicted AlphaFoldDB

No variants for Q57568

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q57568

No associated diseases with Q57568

4 regional properties for Q57568

Type Name Position InterPro Accession
domain Helicase superfamily 1/2, ATP-binding domain 181 - 465 IPR014001
domain DNA2/NAM7 helicase, helicase domain 184 - 437 IPR041677
domain DNA2/NAM7 helicase-like, C-terminal 441 - 633 IPR041679
domain Upf1-like, C-terminal helicase domain 466 - 650 IPR047187

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
5'-3' DNA helicase activity Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQNWFKSGDS LNLVDLYVKK FMDLIEIERR CEMDFHKNEI IKLGKKRENV GRAILNLKGK
70 80 90 100 110 120
FLGESLGCTI VRFGRKKPFK TEISPGDVVL VSKENPLQSD LYANVIYVGK NFIDVAFDVD
130 140 150 160 170 180
VPKWVYKERV RVDLYVNDIT FKRMKEALRE FARKRDKLAY IILGIEHPEK PLREDIKLEF
190 200 210 220 230 240
YDKNLNESQK LAVKKAVLSR DLYLIHGPPG TGKTRTITEV IVQEVKFNKH KVLATADSNI
250 260 270 280 290 300
AADNILEYLI KKYPDLKVVR VGHPTRISKD LIQHSLPYLI ENHEKYQEIL ALREKIKEIK
310 320 330 340 350 360
EQRDKFLKPS PRWRRGMSDE QILKVAKRKK SYRGIPKEKI VSMAEWIIRN KKIKRIINNL
370 380 390 400 410 420
DEITEKIMNE ILAEADVIVA TNSMAGSEIL KGWEFDVIVI DEGSQAMEPS CLIPIVKGRK
430 440 450 460 470 480
LIMAGDHKQL PPTVLSENEE LKKTLFERLI KKYPEFSSIL EIQYRMNEKI MEFPNKMFYN
490 500 510 520 530 540
NKLKADESVK NITLLDLVKE EEIDEVDRDI INEIPVQFIN VEGIERKDKE SPSYYNIEEA
550 560 570 580 590 600
EKVLEIVKKL VKYKIPTNVI TPYDAQVRYL RRLFEEHNID IEVNTVDGFQ GRENEAIVIS
610 620 630 640 650 660
FVRTKNFGFL KDLRRLNVAI TRAKRKLILI GNENLLKQDK VYNEMIKWAK SVEEEHKNKI
IQK