Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q566I3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q566I3-F1 | Predicted | AlphaFoldDB |
No variants for Q566I3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q566I3 | |||||
No associated diseases with Q566I3
1 regional properties for Q566I3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Heat shock protein 70, conserved site | 368 - 382 | IPR018181 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum lumen | The volume enclosed by the membranes of the endoplasmic reticulum. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent protein folding chaperone | Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRPLVCVLWM | FLFALLSSHT | ESVAVMSVDL | GSEWVKVAIV | KPGVPMEIVL | NKESRRKTPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AIALKENERL | FGENALGMAV | KNPKVTFRYF | QDLLGKRLDN | PQVQAFEARF | PEYHLVKDER |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RETVLFKLSE | DLTYSPEELL | GMVLNYSRSL | AEDFAEQPVK | DVVITVPAFF | NQAERRAVLQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAQLSGLKVL | QLINDNTAVA | LNYGVFRRKD | INATAQNVMF | YDMGTRSTIC | TIVTYQTIKT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KDSGTQPQLQ | IRGVGFDRTL | GGLEIDLRLR | DHLAKLFNEQ | KKSKKDVREN | QRAMNKLLKE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ANRVKTILSA | NNDHMAQIEG | LMDDIDFKAK | VTRQELEDLC | ADLFNRVSAP | VQQALASAEM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KMEEIDQVIL | VGGATRVPKV | QEFLLKVVGK | EELSKNINAD | EAAAMGAVYQ | AAALSKAFKV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KPFIVRDAAI | FPIQVEFTRE | VEEENHSKSL | KHNKRILFQR | LAPYPQRKVI | TFNRYTDDFA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FSINYGDLSY | LGPEDLKVFG | SLNLTTVKLN | GVGESFQKRS | DYESKGIKAH | FNMDESGLLT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LDRVEAVFET | VADEKPELES | TLTKLGNTIS | SLFGGGSSVS | ETKENVTDSV | QEEDEVPTEP |
| 610 | 620 | 630 | 640 | ||
| TKEEEQESAD | PADKQQDKEN | NKEKGTSATN | EKEEGKKEEE | KAEPQE |