Q56339

PR
Gene name
flhF (TP_0713)
Protein name
Flagellar biosynthesis protein FlhF
Names
Flagella-associated GTP-binding protein
Species
Treponema pallidum (strain Nichols)
KEGG Pathway
tpa:TP_0713
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-149 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q56339

Entry ID Method Resolution Chain Position Source
AF-Q56339-F1 Predicted AlphaFoldDB

No variants for Q56339

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q56339

No associated diseases with Q56339

3 regional properties for Q56339

Type Name Position InterPro Accession
domain Signal recognition particle, SRP54 subunit, GTPase domain 217 - 417 IPR000897
domain AAA+ ATPase domain 216 - 394 IPR003593
domain Flagellar biosynthesis protein FlhF, GTPase domain 218 - 415 IPR047040

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
bacterial-type flagellum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
SRP-dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELLVEVAPT KEKAIEKIRK KYGDRVNILR TQRNNRSFFF GLIERVSVEI FFSVNSGSQS
70 80 90 100 110 120
SVHEIPSVQS RTRVSAARVE DTEAEKIKIL ESAQRINAKI AQQVEPLISA AKEKKTEKVP
130 140 150 160 170 180
TSPEAVHALT QTLEGMIQKI TNSAPVVIAQ ELQSIQRIEL LLEENDFSFS FIRKSIARLK
190 200 210 220 230 240
DELSYHDLES FEKVESTVLR WIIESVHIQV PPICTGTRNI VLVGPTGVGK TTTLAKLAAF
250 260 270 280 290 300
YFVTEPKRTG IQPRVKIITT DNFRIGAAFQ MERYCELMGL DLCVVQAPVE FLTYMTLYQQ
310 320 330 340 350 360
ETDVVFVDTE GRSPVDGQNI ERMVEYFRAV KNFELEVYLT IDAGSKANDL REVFKQYALF
370 380 390 400 410 420
EYRALIVTKL DETTSIGNLI SALSEARTPI TYITTGQTVP SNLEKASVNL LLSKLKGFKL
430
LAEEMGNDYG DYGSKER