Q56221

PR
Gene name
nqo2 (TTHA0088)
Protein name
NADH-quinone oxidoreductase subunit 2
Names
NADH dehydrogenase I chain 2, NDH-1 subunit 2
Species
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
KEGG Pathway
ttj:TTHA0088
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

18 structures for Q56221

Entry ID Method Resolution Chain Position Source
2FUG X-ray 330 A 2/B/K/T 1-181 PDB
2YBB EM 1900 A 2 1-181 PDB
3I9V X-ray 310 A 2/B 1-181 PDB
3IAM X-ray 310 A 2/B 1-181 PDB
3IAS X-ray 315 A 2/B/K/T 1-181 PDB
3M9S X-ray 450 A 2/B 1-181 PDB
4HEA X-ray 330 A 2/C 1-181 PDB
6I0D X-ray 360 A 2/C 1-181 PDB
6I1P X-ray 321 A 2/C 1-181 PDB
6Q8O X-ray 360 A 2/C 1-181 PDB
6Q8W X-ray 340 A 2/C 1-181 PDB
6Q8X X-ray 351 A 2/C 1-181 PDB
6Y11 X-ray 311 A 2/C 1-181 PDB
6ZIY EM 425 A 2 1-181 PDB
6ZJL EM 430 A 2 1-181 PDB
6ZJN EM 610 A 2 1-181 PDB
6ZJY EM 550 A 2 1-181 PDB
AF-Q56221-F1 Predicted AlphaFoldDB

No variants for Q56221

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q56221

No associated diseases with Q56221

1 regional properties for Q56221

Type Name Position InterPro Accession
domain NuoE domain 77 - 157 IPR042128

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
quinone binding Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGFFDDKQDF LEETFAKYPP EGRRAAIMPL LRRVQQEEGW IRPERIEEIA RLVGTTPTEV
70 80 90 100 110 120
MGVASFYSYY QFVPTGKYHL QVCATLSCKL AGAEELWDYL TETLGIGPGE VTPDGLFSVQ
130 140 150 160 170 180
KVECLGSCHT APVIQVNDEP YVECVTRARL EALLAGLRAG KRLEEIELPG KCGHHVHEVE
V