Q55GS4

PR
Gene name
cdk10 (DDB_G0268480)
Protein name
Probable cyclin-dependent kinase 10
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0268480
EC number
2.7.11.22: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

275-366 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q55GS4

Entry ID Method Resolution Chain Position Source
AF-Q55GS4-F1 Predicted AlphaFoldDB

No variants for Q55GS4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q55GS4

No associated diseases with Q55GS4

3 regional properties for Q55GS4

Type Name Position InterPro Accession
domain Protein kinase domain 7 - 293 IPR000719
active_site Serine/threonine-protein kinase, active site 128 - 140 IPR008271
binding_site Protein kinase, ATP binding site 13 - 36 IPR017441

Functions

Description
EC Number 2.7.11.22 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
cyclin-dependent protein serine/threonine kinase activity Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.
regulation of mitotic cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRSVLSFEKL DSIGEGTYGI VSKGRDKETG RIVALKKVKI GQQDKDGIPL TSLREIQILK
70 80 90 100 110 120
EIKHPNIVSL LEVVIGSTGD KIYLVFEYLE HDVASLIDNI NKPFKLSEIK CFLLQLLRAV
130 140 150 160 170 180
EYLHSHWIIH RDLKCSNLLY GNNGNLKLAD FGLARKFGYP IESITPCMVT LWYRSPELLL
190 200 210 220 230 240
GCQKYSTAVD LWSIGSIFGE LLIGRPLITG NNEVDQIMRI FNLLGEPNEQ IWPGFSSLPN
250 260 270 280 290 300
FKRLNNIPHQ PYNNLRELVP TISDTAFDLL NQLLTYDPTK RITASDAIKH PFFYENPFPQ
310 320 330 340 350 360
SIEMMPKFPT ISKSFKNQNK KQNNNFNNFV QNNQTNQNNQ TNQNNQTNQN NKTSQNNNMD
SYKYSK