Q55DV8
Gene name |
vps37 (DDB_G0269510) |
Protein name |
Vacuolar protein sorting-associated protein 37 |
Names |
ESCRT-I complex subunit VPS37 |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0269510 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q55DV8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q55DV8-F1 | Predicted | AlphaFoldDB |
No variants for Q55DV8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q55DV8 | |||||
No associated diseases with Q55DV8
1 regional properties for Q55DV8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exocyst complex component EXOC2/Sec5, N-terminal domain | 46 - 272 | IPR039481 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| ESCRT I complex | An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes. |
| late endosome membrane | The lipid bilayer surrounding a late endosome. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| protein targeting to membrane | The process of directing proteins towards a membrane, usually using signals contained within the protein. |
| protein targeting to vacuole | The process of directing proteins towards the vacuole, usually using signals contained within the protein. |
| ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKPDLNSLS | IKMKQINLLK | ERFSHTIEVV | KDSTFKIPFL | NVHLLISLPV | NFPNSPPAYF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LEILQTHQPV | SLPPNYQWTQ | ISNLASVTVH | IMEPFIKDSR | ILETLIEQVK | RSQAMQQQQQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QQQQQQRNQQ | AQQQYSPPPP | YKDQPINKQP | AQQQPQPVQQ | KPQQQQNGTN | KIPMIPTEFP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELKSKSVEEL | EELLKNEDSL | NAFIYSYDEV | SELSNRKSKL | LSENERLTKI | TDPLPNDIND |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSANLMTSKQ | KLEELKRKQE | QLQQKKNSIA | DKYSQQNLLE | ILNDSISDLE | SESDNIVHSF |
| 310 | 320 | 330 | |||
| LEGNLELKEF | KKQFKEKRSS | YHSKCANKDL | FFK |