Q55DL0
Gene name |
pyd2 (DDB_G0269246) |
Protein name |
Dihydropyrimidinase |
Names |
DHP, DHPase, Dihydropyrimidine amidohydrolase, Hydantoinase |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0269246 |
EC number |
3.5.2.2: In cyclic amides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q55DL0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2FTW | X-ray | 205 A | A | 1-503 | PDB |
| AF-Q55DL0-F1 | Predicted | AlphaFoldDB |
No variants for Q55DL0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q55DL0 | |||||
No associated diseases with Q55DL0
1 regional properties for Q55DL0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Amidohydrolase-related | 58 - 446 | IPR006680 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.2.2 | In cyclic amides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| dihydropyrimidinase activity | Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| pyrimidine nucleobase catabolic process | The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLRVDQTGTI | LIKNGTVVND | DRYFKSDVLV | ENGIIKEISK | NIEPKEGIKV | VDATDKLLLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GGIDTHTHFQ | LPFMGTVSVD | DFDIGTQAAV | AGGTTFIIDF | VIPTRGQSLL | EAYDQWKKWA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEKVNCDYSL | HVAITWWSEQ | VSREMEILVK | ERGVNSFKCF | MAYKNSFMVT | DQEMYHIFKR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CKELGAIAQV | HAENGDMVFE | GQKKMLEMGI | TGPEGHELSR | PEALEAEATN | RAIVIADSVC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TPVYIVHVQS | IGAADVICKH | RKEGVRVYGE | PIAAGLGVDG | SHMWNHDWRH | AAAFVMGPPI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RPDPRTKGVL | MDYLARGDLD | CVGTDNCTFC | ADQKAMGKDD | FTKIPNGVNG | VEDRMSIVWE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NGVNTGKLTW | CQFVRATSSE | AARIFNIYPR | KGRIDVGCDG | DIVIWDPNQS | KTISKDTHHH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AVDFNIFEGI | KVTGIAVTTI | VAGNIVWSDN | KLSCVKGSGR | FVPRPPFGPV | FDGIEQRDKV |
| 490 | 500 | ||||
| RNELLRKVDR | KPYEDDNTKN | SSK |