Q55DH8

PR
Gene name
catB (DDB_G0269108)
Protein name
Catalase-B
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0269108
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-208 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q55DH8

Entry ID Method Resolution Chain Position Source
AF-Q55DH8-F1 Predicted AlphaFoldDB

No variants for Q55DH8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q55DH8

No associated diseases with Q55DH8

5 regional properties for Q55DH8

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 352 - 360 IPR002226
domain Catalase immune-responsive domain 439 - 504 IPR010582
domain Catalase core domain 22 - 410 IPR011614
active_site Catalase active site 58 - 74 IPR024708
domain Large catalase, C-terminal domain 539 - 683 IPR041399

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

4 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
sorocarp development The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKKLEQLEK FKTNDKNPVY STTNTGVSLS DDANSLKAGP RGPTLLEDFV LREKITHFDH
70 80 90 100 110 120
ERIPERIVHA RGTGAHGYFL SYKDHSKLTK ADFLSKQDKK TPVFIRISTV QGPRGSADTV
130 140 150 160 170 180
RDVHGFAVKF YTDEGNYDLV GNNMPVFFIQ DASSFPDFVH AVKMEPQNEM PTGGSAHDTF
190 200 210 220 230 240
YDFCGLKPES AHSVLWVMSD RGIPISLRHQ QGFGVHSYRF INQEGKSTFV KLHWKPLSGT
250 260 270 280 290 300
CSLLWDEAQK IAGKDCDYHR RRFWEDIESG DFPQWELGAQ LLDEDLQKKF DFDILDPTKL
310 320 330 340 350 360
IPEELTPVIP LGRMVIDRNP DNFFAETEQV AFCVSHVVPG IDFSNDPLLQ GRIFSYLDTQ
370 380 390 400 410 420
LSRLGGPNFN EIPINRPVCP FANNQRDGIH RMTINKGGAS YFPNSIDKGY PLLKEPSANK
430 440 450 460 470 480
GGFRPYPENI SGTKSYDRSE TFEDHFSQAT MFWNSMSQHE KNHIIAAYTF EISKCSRPEV
490 500 510 520 530 540
RTRYVNNILV NIDSVLAEKV AKNLGVKIEP TSTKPIKKIM VKPSPALSQP NLLSGDIVSR
550 560 570 580 590 600
RISVIIEKGV DYDDVINFKD DMEKRGAMVM LVSSTLAQVE CSGGEMLSPK GTIIGNPSIF
610 620 630 640 650 660
FDAVYVPKST EEATKILSDD GNFLHYILEA FKHLKTIAFG GSVSVIKELL RLPQDHGLLL
670 680 690
GNGYKDITEQ FFYSLAHHRV WERESKVSKI PA