Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q55DE2

Entry ID Method Resolution Chain Position Source
AF-Q55DE2-F1 Predicted AlphaFoldDB

No variants for Q55DE2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q55DE2

No associated diseases with Q55DE2

2 regional properties for Q55DE2

Type Name Position InterPro Accession
domain SDA1, C-terminal domain 411 - 754 IPR007949
domain SDA1, N-terminal 57 - 107 IPR012977

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
ribosomal large subunit export from nucleus The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGTRILDLLQ LQNLTKRDPS AYKEEFLLQY QHYLTQLQIF QLKPTKEFKH FSQLVSYLSH
70 80 90 100 110 120
VCVCYPKELS EFPKQISDLL ENNCNNLEPE LRRILAKSLI LMRNRNLLPQ IQMLSLFFKL
130 140 150 160 170 180
FRVHDKPLRS LLYSHIVADI KNTNLKQKNQ KLNRTLQNFM FTMMNDDSEI ASKMSLKVMI
190 200 210 220 230 240
ELFRKKIWHD TKTVNVISNG VFSKNSKILI TTLNFFLHID NPDKPDEEEE DEAVKEKRAK
250 260 270 280 290 300
DNFRKKSLAH RVGKKTKGRI TRLAKSKVDL KKAKQEEDNK LQPNFPAIEL IHDPQGYCDK
310 320 330 340 350 360
LFNVLVKTTE KFETRIMIMN FISRLIYVHK LMVYNFYPFL QKYLQPHQKN ITYLLAVLAQ
370 380 390 400 410 420
SCHELVDPDV LKPLVMTIAK YFVNDGCGSD VIAIGLNTIR SICSRCPLAI DTVLLADLIQ
430 440 450 460 470 480
YREKKEKGVA MASKSLLQFF KDNYPSMLPK KERGKNKTDI GLLAFGHQKV SQGIDGLDLL
490 500 510 520 530 540
MDEELNARLD AIEAGEEFES DDDSDSDSDD EGWEDVNTTT ADDDNNSEWV SDDDDEEGEE
550 560 570 580 590 600
DEEVEDEEDE EEVDEEELED DEEGDWESGE EIEGDDDDDE EWEEVEEEVE EEEEEEIKPT
610 620 630 640 650 660
KKKSQQKEKV EVLRTDDIKV LTDEELIRIR KLRILKEARE NNKQYEDMDQ DDDENGENVH
670 680 690 700 710 720
GLIRPEDLQG AHKKKKEEKL ERIARAKEGR DGGYGSKASR RDKTGKSTTN EYKAKVTKPF
730 740 750
VLTLKTKKVR GKSLKSFRDK QIGQREHSAR QKRGRH