Q55CA0
Gene name |
vps26 (pepA, rcdQ, veg152, DDB_G0269168) |
Protein name |
Vacuolar protein sorting-associated protein 26 |
Names |
|
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0269168 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q55CA0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q55CA0-F1 | Predicted | AlphaFoldDB |
No variants for Q55CA0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q55CA0 | |||||
No associated diseases with Q55CA0
No regional properties for Q55CA0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q55CA0 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| pathogen-containing vacuole | A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides. |
| retromer complex | A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| protein retention in Golgi apparatus | The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known. |
| retrograde transport, endosome to Golgi | The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNFFSNNFGT | PCNVEFELDN | CQNRKTIEVT | QDKGKTEKLF | VFIGNEPVSG | KVSINIKEKT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKIEHTGIRV | EFVGQIELFY | DRGNHYEFTS | LVRELAPAGE | LTENKTFSYD | FSNVEKQYES |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YNGTNVRLRY | FVRLTIGRSF | ASNIVKEYDI | WVINFVKPPE | SNSNIKMEVG | IEDCLHIEFE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YNKSKYHLKD | VIIGKIYFLL | VRIKIKYMEI | ALIKRESTGS | GPNVFNESET | LTKFEIMDGA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PVRGESIPVR | LFLSVFDLTP | TYRSVHNKFS | VKYFLNLALV | DEDDKKYFKQ | QEITLWRRGV |
| 310 | 320 | 330 | 340 | ||
| TKPGLPGSTN | NNNNNNTSNT | NNTNTPQQKV | TESQNEVPEP | ENNSSDESD |