Q55BW2
Gene name |
hdaB (DDB_G0270338) |
Protein name |
Histone deacetylase B |
Names |
DdHdaB, Type-1 histone deacetylase 2 |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0270338 |
EC number |
3.5.1.98: In linear amides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q55BW2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q55BW2-F1 | Predicted | AlphaFoldDB |
No variants for Q55BW2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q55BW2 | |||||
No associated diseases with Q55BW2
No regional properties for Q55BW2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q55BW2 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.1.98 | In linear amides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| histone deacetylase activity | Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. |
| metal ion binding | Binding to a metal ion. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| histone deacetylation | The modification of histones by removal of acetyl groups. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEYNTILNNT | SKTRVCYFFD | QDVGNYFYGP | YHPMKPHRLC | LTNNLVLNYG | LHKKMHLYKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RPADAEDMLK | FHSEDYVDFL | ERVTPENINE | WKDVKRFHIG | EDCPVFPGLY | DYCSIYSGGS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IEGALKLNHR | MYDIAINWSG | GLHHARKDEA | SGFCYVNDIV | LAILELLKFH | ARVLYIDIDV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HHGDGVQEAF | YLTDRVMTVS | FHKFGGDFFP | GTGDIDEIGA | KTGKLYSVNV | PLADGIDDKN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YLNIFKPVIQ | GVMDYYRPSV | IVLQCGADSL | RFDRLGCFNL | TIKGHAECVR | FVKSFNIPTL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLGGGGYTVR | NVARCWTYET | SVCVDTEVNN | ELPYNDYIQF | YSPDFQLIPD | YTGLPFKYEN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ANTKSYLESL | RIKILENLRI | LQWAPSVQIQ | DVPPDIMPID | FDRDEDSKEN | MDKRKKKHND |
| FS |