Q55BR9

PR
Gene name
ddx49 (DDB_G0270396)
Protein name
Probable ATP-dependent RNA helicase ddx49
Names
DEAD box protein 49
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0270396
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

361-508 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q55BR9

Entry ID Method Resolution Chain Position Source
AF-Q55BR9-F1 Predicted AlphaFoldDB

No variants for Q55BR9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q55BR9

No associated diseases with Q55BR9

5 regional properties for Q55BR9

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 152 - 160 IPR000629
domain Helicase, C-terminal 219 - 379 IPR001650
domain DEAD/DEAH box helicase domain 29 - 197 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 23 - 223 IPR014001
domain RNA helicase, DEAD-box type, Q motif 4 - 32 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
nucleic acid binding Binding to a nucleic acid.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDKTFEELG LTTWLVANCK QLGFKAPSNI QANTIPEILK GRDIIASAKT GSGKTASFAI
70 80 90 100 110 120
PILNQLSEDP YGVFAVILTP TRELAVQIGE QFNAIGAPMN VNCSVVIGGI DNVTQALILD
130 140 150 160 170 180
KRPHIIVATP GRLASHLNNG LKIALKFCKF LVLDEADRLL GEDFELEIAS ILEHLPPPEK
190 200 210 220 230 240
RQTLLFSATM TKNLTKLDSI ALNKPFIFED NSKYDTVDTL KQEYIYMPAP TKDCYLVYIL
250 260 270 280 290 300
KKHEGSSAIV FVNNCYAVEA VKGMLNKLDI PSVSLHSFLD QKSRLAALKT FKSGKVKVLV
310 320 330 340 350 360
ATDVASRGLD IPDVQIVINY KLSNSSKDYI HRVGRTARFG RSGRAISFIT PHDVSLIKGI
370 380 390 400 410 420
EEIIKKQLEL YKTDDDEVFR HLKEASTARK IVEIHLDEIE FGVKQKERRT ERNELQKQLK
430 440 450 460 470 480
EVNNKEKFEN NNNDNNNNNK TKTTKPENKK EITKIQEQPS KSTTTTKSIE KKPTTIESKK
490 500
IDKDIKRKEN NFDDGEISLF KKKKITNK