Q55BC0

PR
Gene name
abcA8 (DDB_G0271138)
Protein name
ABC transporter A family member 8
Names
ABC transporter ABCA.8
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0271138
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

458-537 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q55BC0

Entry ID Method Resolution Chain Position Source
AF-Q55BC0-F1 Predicted AlphaFoldDB

No variants for Q55BC0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q55BC0

No associated diseases with Q55BC0

3 regional properties for Q55BC0

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 516 - 750 IPR003439
domain AAA+ ATPase domain 545 - 726 IPR003593
domain ABC-2 type transporter, transmembrane domain 31 - 470 IPR013525

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

4 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATPase-coupled transmembrane transporter activity Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
lipid transporter activity Enables the directed movement of lipids into, out of or within a cell, or between cells.

2 GO annotations of biological process

Name Definition
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
sorocarp development The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSIGETIHRE FIHLKLLLKK NFLVSIRSYF STIIELLSPI VFVLIFYIIY SYGSAVDYSN
70 80 90 100 110 120
VSYEQNLPNC IVSVENRCIN LMFSPMNSTC TVEIMKILAK NNNMEIYNYP TDTGPLPNLE
130 140 150 160 170 180
NTIGFHGGII AMDSLNSTEQ FILAHPNVTL AVVDFENFPL NFTINGVKPN DSLIGFNDFY
190 200 210 220 230 240
DLSFNVLLNL STSGGFIEPV DYSIPVTTSI QKAIYDFYAI NNQKQIPTIN FDSTQFIEYS
250 260 270 280 290 300
SVNVVSLFGG LFYYCAIMIS FIFLLYKVAF EKEKNLKQGM VMMGLSRSMY WLSWVITSFT
310 320 330 340 350 360
IDLIICLLLI AIGAICKLPF FLGTNFLVLL LNFFLFAISS SSMAFFMLTF IGKTKVAIGI
370 380 390 400 410 420
GMAFFIVGSG LQLTFNSLGS LIFQIIYQTD SNGAAFVRVI LFILPMFHFS KVLTDINDKV
430 440 450 460 470 480
QSYPTSQFKI SDLNDNLDGS QYGMDYLVPT TGQSLAYMFI LVIVYLSLSA IIEYALSGGF
490 500 510 520 530 540
SFKTVKHINV PHFDDQDVAN ATNRSLDPSN KSPFIIRGLS KTFNKFLRPS KSVHALKYLS
550 560 570 580 590 600
LDIQEGTVLG LLGSNGAGKS TTIGILTGIH SPTSGDAIIY GHSVVKDIHS VRKITSVVPQ
610 620 630 640 650 660
DDILWLELTA MEHLHLFAEL KGIPVRERDF QIAKVLEQVK LTKVANDQCS TFSGGMKRRL
670 680 690 700 710 720
SVAIGCIGDP KIIFMDEPTT GLDPRSKRRI YTLVKEIKKD KVIILTSHDM HEIEILAQNL
730 740 750 760 770 780
VILNDGIMVC NGNALQLKTK YGEGYSVQVI AKSLEVIPEI INFVTSSLPY CRFLKQSALQ
790 800 810 820 830
LNFGFPINTD PKIIVNFFKR LESITKDENN NLMRDWSISH SNMDDVFIKV SNKPKLQ