Q556Y9

PR
Gene name
mad2l1-1 (mad2a-1, DDB_G0273201;, mad2l1-2, mad2a-2, DDB_G0273727)
Protein name
Mitotic spindle assembly checkpoint protein MAD2A
Names
Mitotic arrest deficient 2-like protein 1, MAD2-like protein 1
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0273727
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

79-150 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q556Y9

Entry ID Method Resolution Chain Position Source
AF-Q556Y9-F1 Predicted AlphaFoldDB

No variants for Q556Y9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q556Y9

No associated diseases with Q556Y9

1 regional properties for Q556Y9

Type Name Position InterPro Accession
domain HORMA domain 14 - 196 IPR003511

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome, centromere, kinetochore
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
kinetochore A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
cheating during chimeric sorocarp development Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.
mitotic spindle assembly checkpoint signaling A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint, that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQAAVASKTN ISLKGSTEIV TEFFSYSINT ILFQRGLYPP ESFTRVAKYG LPILVTNDQS
70 80 90 100 110 120
LKDYLDNVLK QLSEWLLSGD VQKLVLVITD IVTKEVLERW VFDVTTDIPK EGEAPRQKPE
130 140 150 160 170 180
KEIMNEIQAI IRQITASVTF LPLLPNACTF DLLVYTSKDL AVPQKWEESD PKFITNSQQV
190 200
KLRSFTTTIH KVESMVAYKI SND