Q54YS6

PR
Gene name
pnpo (DDB_G0278107)
Protein name
Pyridoxine-5'-phosphate oxidase
Names
Pyridoxamine-phosphate oxidase
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0278107
EC number
1.4.3.5: With oxygen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54YS6

Entry ID Method Resolution Chain Position Source
AF-Q54YS6-F1 Predicted AlphaFoldDB

No variants for Q54YS6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54YS6

No associated diseases with Q54YS6

3 regional properties for Q54YS6

Type Name Position InterPro Accession
domain Pyridoxamine 5'-phosphate oxidase, putative 51 - 129 IPR011576
domain Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal 184 - 227 IPR019576
conserved_site Pyridoxamine 5'-phosphate oxidase, conserved site 194 - 207 IPR019740

Functions

Description
EC Number 1.4.3.5 With oxygen as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
pyridoxamine-phosphate oxidase activity Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide.

1 GO annotations of biological process

Name Definition
pyridoxine biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSINLDNEEL KNEDLVANMR KDYRMGELKE EGLLESPFKM FDMWLTQEIE LKNEGAEPNA
70 80 90 100 110 120
FTLATCSIER KPSARVVLLK HFDHQGFVFY TNYNSRKSKE LSENPFASMT FLWTQKQVRI
130 140 150 160 170 180
EGSVEKVDRL ESEKYFKSRP RSSQIGAWVS EFQSSEVTKQ HLEEKTIEME NKFKDQEVPL
190 200 210 220
PPFWGGWRIK PYAFEFWQGK SGRIHDRFKY VPTDSNNDNW ITKRLSP