Q54Y55

PR
Gene name
shkC (DDB_G0278409)
Protein name
Dual specificity protein kinase shkC
Names
SH2 domain-containing protein 3, SH2 domain-containing protein C
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0278409
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

164-172 (Activation loop from InterPro)

Target domain

24-284 (Protein kinase domain)

Relief mechanism

Assay

185-189 (Activation loop from InterPro)

Target domain

24-284 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q54Y55

Entry ID Method Resolution Chain Position Source
AF-Q54Y55-F1 Predicted AlphaFoldDB

No variants for Q54Y55

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54Y55

No associated diseases with Q54Y55

2 regional properties for Q54Y55

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 183 - 363 IPR001251
domain CRAL/TRIO, N-terminal domain 108 - 165 IPR011074

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
protein tyrosine kinase activity Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSGLGSSYP EERSGPPEIR PEEINFEELI GTGSFGKVYK GRCRQKAVAV KLLHKQNFDA
70 80 90 100 110 120
ATLSAFRKEV HLMSKIYHPN ICLFMGACTI PGRCVIVTEL VPKGNLETLL HDQKIQLPLY
130 140 150 160 170 180
LRMRMARDAA LGINWLHESN PVFVHRDIKS SNLLVDENMR VKICDFGLSA LKQKHKMLKD
190 200 210 220 230 240
QSSAKGTPLY MAPEVMMFKE FNESSDVYSF GIVLWEILTR KEPFSHHREL EKFREAVCVK
250 260 270 280 290 300
HERPPIPNDC LDSLRRLIEK CWDKEPISRP SFKEIISALD HVIIDAAISD LNGRDFWKKS
310 320 330 340 350 360
FLTEQEVPWE AFIDALCNWS KAPARNQCDK TSIDYLNIKC LKAVLAESPK SEGTGVETVV
370 380 390 400 410 420
NIEKFGKILE FFGPVPEPAP GHSIMDTVRE ILSQKWFHGD LDTTEAASRL NGQPIGSFLI
430 440 450 460 470 480
RFSSTNAGCF TISQVVDGGS IKHQRVSRQG VKFNYQNVIY NSLIEIVSKN GGGANGDVKL
490 500
DSQLGVPNYK FMSLFCVLNK ESEVYQ