Q54VS7

PR
Gene name
mcfK (slc25a19, DDB_G0280161)
Protein name
Probable mitochondrial thiamine pyrophosphate carrier
Names
Mitochondrial substrate carrier family protein K, Solute carrier family 25 member 19 homolog
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0280161
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-43 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54VS7

Entry ID Method Resolution Chain Position Source
AF-Q54VS7-F1 Predicted AlphaFoldDB

No variants for Q54VS7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54VS7

No associated diseases with Q54VS7

6 regional properties for Q54VS7

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 345 - 512 IPR000795
domain Small GTP-binding protein domain 348 - 504 IPR005225
domain Translation initiation factor IF-2, N-terminal 269 - 320 IPR006847
domain Initiation factor 2 associated domain, bacterial 63 - 101 IPR013575
domain Translation initiation factor IF- 2, domain 3 621 - 735 IPR023115
domain Translation initiation factor IF-2, domain II 520 - 614 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
thiamine transmembrane transporter activity Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.

1 GO annotations of biological process

Name Definition
thiamine pyrophosphate transmembrane transport The process in which thiamine pyrophosphate is transported across a membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIITTSNDED KKTNVFVELA AGSFSGALTR FIVAPLDVVK IRLQLQRTQL NNNSNNNNKI
70 80 90 100 110 120
IGKENVNYRG IINTMSKVIR EEGIRSLWKG NFSAELLWVT YAAIQFSTYN EIIGILDPEY
130 140 150 160 170 180
RKHQQRTDKD KPNYKPSSSI TMIGGASAGI LSTIVSYPFD IIRTNIVNNH NKTNFKQTFK
190 200 210 220 230 240
TIIARNGGYS NLFSGINSSL FQIVPQMGFQ FTFYETFKFI SNKYTSSVNN NNNNPLNQFT
250 260 270 280 290 300
CGLLSGAISK FLVLPFDVVK KRLQVNEKVG YGMKSCFRDL YFNEGGVKAF FKGGTPGIVK
310 320
AGLAAALSFT FFEQSKRILL NKQ