Q54UM1

PR
Gene name
hop2 (DDB_G0280989)
Protein name
Homologous-pairing protein 2 homolog
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0280989
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

73-158 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54UM1

Entry ID Method Resolution Chain Position Source
AF-Q54UM1-F1 Predicted AlphaFoldDB

No variants for Q54UM1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54UM1

No associated diseases with Q54UM1

2 regional properties for Q54UM1

Type Name Position InterPro Accession
domain Homologous-pairing protein 2, winged helix domain 10 - 67 IPR010776
domain Leucine zipper with capping helix domain 158 - 212 IPR040661

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
condensed nuclear chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
DNA recombinase auxiliary factor complex A protein complex that binds to a recombinase and incrseases its activity.

2 GO annotations of molecular function

Name Definition
double-stranded DNA binding Binding to double-stranded DNA.
recombinase activator activity Binds to and increases the activity of a recombinase.

3 GO annotations of biological process

Name Definition
homologous chromosome pairing at meiosis The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.
meiotic joint molecule formation The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.
meiotic strand invasion involved in reciprocal meiotic recombination The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKITKKDE VEENILNLIN KANRPYNYQM IEAAFPSMGK TQIVKTLKSL GEQGKLTFKE
70 80 90 100 110 120
YNKAIIYWRI QDTGPKLDEQ GYEIPQESIH DLNRKLDGIN RQLEVEQDTL KSLISQSKQL
130 140 150 160 170 180
NNQLSDEQIQ KEVNQLSTEN KELESKLLTF QTKEIMSDKD KQRLDDTIKK ARSEWVKRKA
190 200 210 220 230 240
LFRDILDQVL ERSNKKKKDL QEDIGWETDE DLKIQMIPDY SKPLSQQTLS STNDESPFKK
QKK