Q54T59

PR
Gene name
sec23 (DDB_G0281985)
Protein name
Protein transport protein SEC23
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0281985
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

262-332 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q54T59

Entry ID Method Resolution Chain Position Source
AF-Q54T59-F1 Predicted AlphaFoldDB

No variants for Q54T59

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54T59

No associated diseases with Q54T59

6 regional properties for Q54T59

Type Name Position InterPro Accession
domain Zinc finger, Sec23/Sec24-type 54 - 93 IPR006895
domain Sec23/Sec24, trunk domain 124 - 376 IPR006896
domain Sec23/Sec24, helical domain 505 - 603 IPR006900
domain Gelsolin-like domain 619 - 705 IPR007123
domain Sec23/Sec24 beta-sandwich 386 - 486 IPR012990
domain Sec23, C-terminal 597 - 717 IPR037550

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
endoplasmic reticulum exit site An endoplasmic reticulum part at which COPII-coated vesicles are produced.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

2 GO annotations of molecular function

Name Definition
GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
COPII-coated vesicle cargo loading The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNFDQSEDRD GVRFSWNVWP TSRVEATKNL LVPLGCLYTP LHQSPEITQV PYPPLRCKGI
70 80 90 100 110 120
CNAILNPYCT IAPPYKTWVC PFCLQHNQFP PHYAGISDLN RPAELLPHVT TIEYQLPTAE
130 140 150 160 170 180
TPLPIYLFVV DVCVPDDELQ SLTDSLTMSL SLIPENSYVG LITFGSMVQL YELGFTSCPK
190 200 210 220 230 240
SYVFRGDPPT NTFKIANLMQ KVGSPETMNL QSKRFLVPVS ECEFHLTSIL EEIQKDPCRV
250 260 270 280 290 300
ASDKRPLRAT GMAFSVANAL LSTVASNMGG RIMAFIGGPA TTGPGLVVSE DLREPIRSHH
310 320 330 340 350 360
EVIKGKTKYT SKAYQFYKSI GERSVASGHA IDIFSCSLDQ VGLYEMREMV KLTGGYMVLA
370 380 390 400 410 420
DSFDHPMFTQ SFQKIFTRED NAFKMGYNAE VQVCTSMSLK VCGAIGHMSS RNNKTSCVGE
430 440 450 460 470 480
NEIGIGGTSS WKVCALDQNS TFAFYFEIAN TQQNAPEQLG LVQFITSYQN SLGKQILRVS
490 500 510 520 530 540
TIRREWVQHT MEQQQNITML ANGFDQETSA VLMARLAVFK AETEELPDIT RWLDKMLIKL
550 560 570 580 590 600
VSKYADYRRD DPTSFKLVSN FSIYPHFMFH LRRSSFLQVF NSSPDESSFY RFMLNRENVS
610 620 630 640 650 660
NSLIMIQPTL EKYSFSGPPH PEVLSASSIS IDSILLLDTF FHVLIFHGET IAQWRKAGYD
670 680 690 700 710 720
KDPQHQNFRD LLQAPRDDAA HILKERFPYP RYIVCDQHSG EARFLLATID PNITHTSNTP
730 740
QDPSKGEIVF TDDVNLHVFL EHLKKFAVQS