Q54SJ5

PR
Gene name
DDB_G0282429
Protein name
Probable myosin light chain kinase DDB_G0282429
Names
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0282429
EC number
2.7.11.18: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

177-199 (Activation loop from InterPro)

Target domain

38-290 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q54SJ5

Entry ID Method Resolution Chain Position Source
AF-Q54SJ5-F1 Predicted AlphaFoldDB

No variants for Q54SJ5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54SJ5

No associated diseases with Q54SJ5

3 regional properties for Q54SJ5

Type Name Position InterPro Accession
domain Protein kinase domain 38 - 290 IPR000719
active_site Serine/threonine-protein kinase, active site 154 - 166 IPR008271
binding_site Protein kinase, ATP binding site 44 - 67 IPR017441

Functions

Description
EC Number 2.7.11.18 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
myosin light chain kinase activity Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDRMDSSDEE IDNISDDELQ SGDEIEVESS NSPLRLNYIL GNEIGRGAFS IVREATSRAT
70 80 90 100 110 120
GTKVAIKSIN TRFIKNKLLM REIEIMKKVG DHPNILKLYE VYETTKHLHL VLELVTGGEL
130 140 150 160 170 180
FDKIVQRGEY SEQDASKIVR QIVSAVGHLH ANGIAHRDLK PQNLLCAGEE GDDIRVADFG
190 200 210 220 230 240
LSKIFGDGDY LETCCGSPEY VAPEVLECKP YDKACDLWSV GVITYVLLTG CFPFWDKNNA
250 260 270 280 290 300
VLYEKIRNVD YGWPEGLEVS NEAKDLVSHL IEKNPEKRFT FEQCLIHPWV TGEGVSNARK
310
IKPFQQQQPN NR