Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q54R98

Entry ID Method Resolution Chain Position Source
AF-Q54R98-F1 Predicted AlphaFoldDB

No variants for Q54R98

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q54R98

No associated diseases with Q54R98

2 regional properties for Q54R98

Type Name Position InterPro Accession
domain Protein kinase domain 312 - 586 IPR000719
binding_site Protein kinase, ATP binding site 318 - 348 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSQNWKNCF NKKAIEVIEI HRSQETITVE TVNNEDKIKN NISKPKIKVH KKPIIKSISK
70 80 90 100 110 120
LKLQPKFSRY NDIIDYSIDF NCNKNYFLKQ DKVSGNTFIH VFCEKRESKI NLESDIENLK
130 140 150 160 170 180
CLGKETIEAR NNNKEIALFS TLKNQCLGLK IMHELISRNV MFIDDNGKDE LLVKCLEEGR
190 200 210 220 230 240
VDMVKYLITV DINLISKLKR ICQITQLSLE TLQFVELINS EYEKIVEIGL KSAGREYIKL
250 260 270 280 290 300
FFIQFILGNF SKESIIQTID EYKLPPIPKE IEDFFFVYNY QMCDFVKLTE IKPRYLNEIS
310 320 330 340 350 360
KINIYPIGQV SIERRNELGR GGNGTVYSGV LKEIDSQGNE ISIPVAIKIP TQFYKSKLVE
370 380 390 400 410 420
VYKELAIHQK INGICGPKLF GCVKLNVGFG IIIERFDCSL HDYIQNNNID FDLFFELALK
430 440 450 460 470 480
MVITIRNLHK CHLNEIFHRD IKPHNWLVKK TKDELVVVLS DFGLSRENSE TNENTLQKYR
490 500 510 520 530 540
GTSVFIPPEL NDNILYNEKS DIYSLGVSFM MLLYKVVYGK MENPFYEFKI SKMEYFKTVV
550 560 570 580 590 600
ALENFLVPIV PTFLPDSFKE FLFSTMNRIY TCRPNSEECV ERLITLKTEY ENDKTKWQVN
610 620 630 640 650 660
SAIIQKEKSL LTDSIISQQL KLMNQVKKFV QENDKFVFLK KTKLFFSESE IKQYLLSIIK
CQE