Q54QP0
Gene name |
nrde2 (DDB_G0283719) |
Protein name |
Nuclear exosome regulator NRDE2 |
Names |
Protein NRDE2 homolog |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0283719 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q54QP0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q54QP0-F1 | Predicted | AlphaFoldDB |
No variants for Q54QP0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q54QP0 | |||||
No associated diseases with Q54QP0
4 regional properties for Q54QP0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | HAT (Half-A-TPR) repeat | 348 - 380 | IPR003107-1 |
| repeat | HAT (Half-A-TPR) repeat | 428 - 467 | IPR003107-2 |
| repeat | HAT (Half-A-TPR) repeat | 864 - 899 | IPR003107-3 |
| repeat | HAT (Half-A-TPR) repeat | 1221 - 1254 | IPR003107-4 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nuclear speck | A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of RNA catabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. |
| post-transcriptional gene silencing by RNA | A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation. |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSHSKKSLFA | AYSNDDDGDG | DGDDLYLEEH | QKVTSTNTPS | SSWFSNSSYK | EKQENVIDTV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TSKTQLKRAS | DFFNLDSDNT | FSSPPPPSSS | PPLYSKTEKK | NNDKVKIIMK | KRSFIDSSSD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DNSDDDDNDS | SSSDQDSSDD | DSGGFTYNRK | KYKKEQQQQE | NEENEENERK | NRKKEKKKKR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KDKKFKNDDK | SMMIISNENS | ENYSDNSSYF | IEKTGDKVFS | SRTSTPNYNY | DNSFILGMSD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YKIGFSKKEG | YQIEPISLTS | FNKQQINNRY | FTKPSSSSSS | SSQSQQQLIT | VITKRKEIEE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IEKVKPISNI | KDPSKSNDDE | IKLIVLNENN | HDNDDDDNDD | DDNETLERKT | LKKNSELNKL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VEQYPNNIEY | WIDLVKFQEN | FQQFSRNVNK | SKTSMYEKQL | SIYRNSLLHN | PDSEILTIEY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LKLASKLWDQ | QKVLDLWNKV | LSSSSSSSSS | SIISEKLWKE | YIEFCLSNFN | DFKIEKIKET |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IITIIRKMLV | KRRSFKVKDY | NFMENISNLE | ESILQFISQL | SKLLNQAGFS | ERVIGIYQSL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IEFNCFEPIQ | LSNETQATLL | KEFKSYWSSL | DYPKIGNPNS | IGWSKSFTIL | LNNSINNNNN |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KNNNNNNNNN | NNNNNNNNNN | NNNNNNNNNN | NNNNNNNNNN | MDLDNLDNLS | IEEIEKLLKE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| QEDQENQDNE | NIFNITHKSK | DLNEDDDNEN | NNNNQEEQED | NDSNSNDNDN | NNNKFNTWGK |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KEIELDELKW | KPLDINNNLE | VNKEVNENDT | ERVVLFNDFY | ELLFRFVKEE | NKLELVFQFL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| EFLGVPISLL | DDKIQPRYSF | YHPQRRDSIN | SIHNENIISL | LFKDLKQQPS | PPSPSPEYPN |
| 850 | 860 | 870 | 880 | 890 | 900 |
| WFKTFDKFSN | NNNNSQNLLG | LSDDKIKFID | SIYKLILENS | NGIKLKEKLY | VSYIMFKASI |
| 910 | 920 | 930 | 940 | 950 | 960 |
| DINDAKVYTK | SLCEKFKNLI | YFDIFASLEL | KSGKTQQART | IYQTTCFYIN | QLINQQAQQQ |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| QQQLQIDLVY | REYLFMELNL | IYQTIEKDPQ | ILKRFIKSNH | KPIELFFTPL | HILQCYLDGN |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| YKQYSSSTFN | LNTINQFLNQ | LNLKFLQKLQ | QQQQQQQQNS | SSSSSSSSSS | SSSSSSSSSS |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| VDFLLCYCIF | ELLSNGFDGF | LILFKRITSS | STNDYLKIFS | IQHELLTIRC | IDMVTKIAPL |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| IGTDPKRIKN | LIIDSLNQYY | DHPKLLSLFL | NWESKNQLIN | RIRIYFDLNS | INNINNNNGG |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| DDGGSSIFWL | FAIKFESNRI | GAAQRIKSLF | EKAISTTQKH | NIIFWKLYIE | FEINRGRLKI |
| 1270 | 1280 | 1290 | 1300 | 1310 | |
| AKSIYYRSIK | QLPFSKQIWL | LPFTNSKLSL | IFNNQEFNEI | INLINEKGIR | LRILTPKVSN |