Q54PX7
Gene name |
pcid2 (DDB_G0284241) |
Protein name |
PCI domain-containing protein 2 homolog |
Names |
CSN12-like protein |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0284241 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q54PX7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q54PX7-F1 | Predicted | AlphaFoldDB |
No variants for Q54PX7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q54PX7 | |||||
No associated diseases with Q54PX7
1 regional properties for Q54PX7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Proteasome component (PCI) domain | 243 - 424 | IPR000717 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| transcription export complex 2 | A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| double-stranded DNA binding | Binding to double-stranded DNA. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| poly(A)+ mRNA export from nucleus | The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm. |
| post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery | The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed. |
| transcription elongation by RNA polymerase II promoter | The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAELTNHFNK | VNELLNDWDG | VGLSHELSMT | ELITSILNSI | NHNSHSGMSN | QKKQQIQAKV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NQIKKTDLVV | KRQQDIDTLC | ANKIQHNYNE | IVAYRLRSIS | SLLDSKYYDA | FRYLIEAINS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FVKVFELWSQ | NILWRLSLDL | RLMAELATLN | VGSNDSNNSN | NNVTIDYFEE | ASRTLLSKCF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QAANADRTPN | LAESKKNAAL | GVVNQLFQIY | FKINNLKLCK | NLIKTMESPG | FPTLESYPLN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QVITYRFFNG | RLSVFNGQYK | KAQEELLYAF | NKCPNDSIKN | KRLILLFLVP | MQLEQCKFPK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KSLLEKFKLT | QFIDIVQSIK | SGNIKQFNEC | LSTHQNFFIS | KGIYLILEKL | KIIVYRNLFK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KVHLITTGQR | IPIGNFVSAL | KWMENDAIDI | DETECILSNL | IYNGYLKGYI | SHKVALVVSP |
| TNPFPKLPLN |